Mycobacterium tuberculosis infection and resistance to rifampicin with GeneXpert®MTB/RIF: a single-center experience on bronchoalveolar lavage samples in renal failure patients

被引：0

作者：

Iqbal, Maria ^{[1
]}

Jamil, Bushra ^{[2
]}

Bukhari, Mohammad Tauseef Mukhtar ^{[3
]}

Saeed, Azhar ^{[1
]}

Bhatti, Dawar Majeed ^{[1
]}

Muhammad, Ateeq Ur Rehman ^{[1
]}

Hussain, Zakir ^{[1
]}

Abbasi, Shahid Ahmad ^{[1
]}

Ahmed, Ammar ^{[1
]}

机构：

[1] Al Sayed Hosp Pvt Ltd, Rawalpindi, Pakistan

[2] NUMS, Rawalpindi, Pakistan

[3] Al Sayed Hosp Pvt Ltd, Yusra Med & Dent Coll, Rawalpindi, Pakistan

来源：

JOURNAL OF THE PAKISTAN MEDICAL ASSOCIATION | 2019年 / 69卷 / 02期

关键词：

GeneXpert (R) MTB/RIF; bronchoalveolar lavage; Mycobacterium tuberculosis; End-stage renal disease; TRANSPLANT RECIPIENTS; MTB/RIF;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Patients with end-stage renal disease (ESRD) are immunocompromised and are more at risk to develop and acquire Mycobacterium tuberculosis (MTB) infection. However, risk assessment is uncertain. The objective of current research was to study the frequency of MTB infection in ESRD patients. Forth is pur pose, bronchoalveolar lavage (BAL) samples were evaluated for the presence of MTB by using GeneXpert (R) MTB/RIF test. We analysed 350 clinical samples of BAL collected from a tertiary care hospital in Pakistan, from September, 2015 to July, 2016. We performed the GeneXpert (R) test on each sample. According to our results prevalence of MTB was observed in 1.7% of bronchoalveolar lavage (BAL) samples taken from patients with chronic kidney diseases. All the positive samples were susceptible to rifampicin. There is a low prevalence of MTB infection (pulmonary tuberculosis) in patients with chronic kidney disease in our setup. Suspected patients can be diagnosed by using GeneXpert (R) MTB/RIF testing on bronchoalveolar lavage samples.

引用

页码：244 / 245

页数：2

共 10 条

[1] High prevalence of multidrug-resistant tuberculosis among patients with rifampicin resistance using GeneXpert Mycobacterium tuberculosis/rifampicin in Ghana [J].