The Role of MicroRNAs in Diagnosis and Treatment of Schizophrenia

Schizophrenia is a clinical disease that usually progresses with hallucinations or delusions, varies to other functional impairments, and progresses with chronic and frequent relapses. MicroRNAs (miRNAs) that are post-transcriptional regulators of gene expression are small, endogenous, non-coding, highly conserved single-stranded RNA molecules with a length of 22-25 nucleotides. Studies conducted in recent years have demonstrated that miRNAs are implicated in the pathogenesis of schizophrenia, and might be used as potential biomarkers and are significant for the treatment of these kind of disorders. In the present study, the relationship between schizophrenia and microRNAs and its significance in terms of diagnosis and treatment will be clarified, in the research, "document scanning-literature scanning" method was used as a way of data collection.