The Role of MicroRNAs in Diagnosis and Treatment of Schizophrenia

被引：0

作者：

Kagizman, Elif Betul ^{[1
]}

Avsar, Orcun ^{[1
]}

机构：

[1] Hitit Univ, Dept Mol Biol & Genet, Corum, Turkey

来源：

CYPRUS TURKISH JOURNAL OF PSYCHIATRY AND PSYCHOLOGY | 2022年 / 4卷 / 03期

关键词：

Schizophrenia; miRNA; Biomarker; SMALL RNAS; CIRCULATING MICRORNAS; NUCLEAR EXPORT; EXPRESSION; TARGET; NEUROPATHOLOGY; ASSOCIATION; BIOGENESIS; MATURATION; PLASTICITY;

D O I：

10.35365/ctjpp.22.3.08

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Schizophrenia is a clinical disease that usually progresses with hallucinations or delusions, varies to other functional impairments, and progresses with chronic and frequent relapses. MicroRNAs (miRNAs) that are post-transcriptional regulators of gene expression are small, endogenous, non-coding, highly conserved single-stranded RNA molecules with a length of 22-25 nucleotides. Studies conducted in recent years have demonstrated that miRNAs are implicated in the pathogenesis of schizophrenia, and might be used as potential biomarkers and are significant for the treatment of these kind of disorders. In the present study, the relationship between schizophrenia and microRNAs and its significance in terms of diagnosis and treatment will be clarified, in the research, "document scanning-literature scanning" method was used as a way of data collection.

引用

页码：278 / 287

页数：10

共 94 条

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