Diabetes insipidus in children

被引:5
作者
Jain, Vandana [1 ]
Ravindranath, Aathira [2 ]
机构
[1] All India Inst Med Sci, Dept Pediat, Div Pediat Endocrinol, New Delhi 110029, India
[2] All India Inst Med Sci, Dept Pediat, New Delhi 110029, India
关键词
antidiuretic hormone; apelin; aquaporin; diabetes insipidus; hypernatremia; polyuria; water deprivation test; WATER CHANNELS; YOUNG-ADULTS; AQUAPORIN-2; ANTIBODIES; DIAGNOSIS; APELIN;
D O I
10.1515/jpem-2014-0518
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Diabetes insipidus (DI) is one of the common disorders affecting sodium and water homeostasis, and results when ADH is either inadequately produced, or unable to negotiate its actions on the renal collecting tubules through aquaporins. The diagnostic algorithm starts with exclusion of other causes of polyuria and establishing low urine osmolality in the presence of high serum osmolality. In this paper, we have reviewed the diagnosis, etiology and management of DI in children, with special emphasis on recent advances in the field.
引用
收藏
页码:39 / 45
页数:7
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