IL-26 AMPs up the TH17 arsenal

被引:6
作者
Lee, Jacob S. [1 ]
Cua, Daniel J. [1 ]
机构
[1] Merck Res Lab, Pathways Inflammat, Palo Alto, CA 94304 USA
关键词
ANTIMICROBIAL PEPTIDES; CELLS; INDUCTION;
D O I
10.1038/ni.3256
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A previously unknown function for T(H)17 cell-derived IL-26 as a direct antimicrobial agent and activator of DNA-sensing innate immunity is now reported.
引用
收藏
页码:897 / 898
页数:2
相关论文
共 50 条
  • [21] Leishmania infection and study of cytokines IL-17, IL-22 (Th17 cells)
    Seyyedan, Jasbi Ehsan
    Miramin, Mohammadi Akram
    Eskandari, Ebrahim
    CLINICAL BIOCHEMISTRY, 2011, 44 (13) : S164 - S165
  • [22] TH17 Cell Induction and Effects of IL-17A and IL-17F Blockade in Experimental Colitis
    Schmidt, Esben Gjerloff Wedebye
    Larsen, Hjalte List
    Kristensen, Nanna Ny
    Poulsen, Steen Seier
    Pedersen, Anne Marie Lynge
    Claesson, Mogens Helweg
    Pedersen, Anders Elm
    INFLAMMATORY BOWEL DISEASES, 2013, 19 (08) : 1567 - 1576
  • [23] T helper 17 (Th17) cells and interleukin-17 (IL-17) in cancer
    Chang, Seon Hee
    ARCHIVES OF PHARMACAL RESEARCH, 2019, 42 (07) : 549 - 559
  • [24] Bringing in the Cavalry: IL-26 Mediates Neutrophil Recruitment to the Lungs
    Griffiths, Kristin L.
    Khader, Shabaana A.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2014, 190 (10) : 1079 - 1080
  • [25] IL-26 inhibits hepatitis C virus replication in hepatocytes
    Beaumont, Elodie
    Larochette, Vincent
    Preisser, Laurence
    Miot, Charline
    Pignon, Pascale
    Blanchard, Simon
    Hansen, Bjorn-Thore
    Dauve, Jonathan
    Poli, Caroline
    Poranen, Minna M.
    Lamourette, Patricia
    Plaisance, Marc
    Morel, Alain
    Fickenscher, Helmut
    Jeannin, Pascale
    Roingeard, Philippe
    Delneste, Yves
    JOURNAL OF HEPATOLOGY, 2022, 76 (04) : 822 - +
  • [26] The Role of Th17/IL-17 in the Pathogenesis of Primary Nephrotic Syndrome in Children
    Wang, Li
    Li, Qiu
    Wang, Lijia
    Li, Cuicui
    Yang, Haiping
    Wang, Xiaoli
    Tao, Hong
    KIDNEY & BLOOD PRESSURE RESEARCH, 2013, 37 (4-5) : 332 - 345
  • [27] The Th17/IL-17 Axis and Kidney Diseases, With Focus on Lupus Nephritis
    Paquissi, Feliciano Chanana
    Abensur, Hugo
    FRONTIERS IN MEDICINE, 2021, 8
  • [28] Clinical Consequences of Targeting IL-17 and TH17 in Autoimmune and Allergic Disorders
    Robinson, Keven M.
    Manni, Michelle L.
    Biswas, Partha S.
    Alcorn, John F.
    CURRENT ALLERGY AND ASTHMA REPORTS, 2013, 13 (06) : 587 - 595
  • [29] The Th17/IL-17 Axis and Host Defense Against Fungal Infections
    Tangye, Stuart G.
    Puel, Anne
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2023, 11 (06) : 1624 - 1634
  • [30] Osteoimmunology in periodontitis; a paradigm for Th17/IL-17 inflammatory bone loss
    Ikeuchi, Tomoko
    Moutsopoulos, Niki M.
    BONE, 2022, 163