Unravelling the nonmotor mysteries of Parkinson disease

被引：27

作者：

Chaudhuri, K. Ray ^{[1
]}

Sauerbier, Anna ^{[1
]}

机构：

[1] Kings Coll London, Maurice Wohl Clin Neurosci Inst, London SE5 9RT, England

来源：

NATURE REVIEWS NEUROLOGY | 2016年 / 12卷 / 01期

关键词：

DIAGNOSIS; CRITERIA;

D O I：

10.1038/nrneurol.2015.236

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Parkinson disease (PD) is now regarded as a mixed motor, nonmotor and multiorgan disorder rather than a pure movement disorder. Nonmotor symptoms (NMS) have underpinned this conceptual change, and new criteria for clinical and prodromal diagnosis of PD, incorporating a range of NMS, have recently been published.

引用

页码：10 / 11

页数：2

共 10 条

[1] MDS research criteria for prodromal Parkinson's disease [J].

Berg, Daniela ;

Postuma, Ronald B. ;

Adler, Charles H. ;

Bloem, Bastiaan R. ;

Chan, Piu ;

Dubois, Bruno ;

Gasser, Thomas ;

Goetz, Christopher G. ;

Halliday, Glenda ;

Joseph, Lawrence ;

Lang, Anthony E. ;

Liepelt-Scarfone, Inga ;

Litvan, Irene ;

Marek, Kenneth ;

Obeso, Jose ;

Oertel, Wolfgang ;

Olanow, C. Warren ;

Poewe, Werner ;

Stern, Matthew ;

Deuschl, Guenther .

MOVEMENT DISORDERS, 2015, 30 (12) :1600-1609

[2] Non-motor symptoms of Parkinson's disease: diagnosis and management [J].

Chaudhuri, KR ;

Healy, DG ;

Schapira, AHV .

LANCET NEUROLOGY, 2006, 5 (03) :235-245

[3] Imaging amyloid deposition in Lewy body diseases [J].

Gomperts, S. N. ;

Rentz, D. M. ;

Moran, E. ;

Becker, J. A. ;

Locascio, J. J. ;

Klunk, W. E. ;

Mathis, C. A. ;

Elmaleh, D. R. ;

Shoup, T. ;

Fischman, A. J. ;

Hyman, B. T. ;

Growdon, J. H. ;

Johnson, K. A. .

NEUROLOGY, 2008, 71 (12) :903-910

[4] The Prodromal Phase of Sporadic Parkinson's Disease: Does It Exist and If So How Long Is It? [J].

Hawkes, Christopher H. .

MOVEMENT DISORDERS, 2008, 23 (13) :1799-1807

[5] ACCURACY OF CLINICAL-DIAGNOSIS OF IDIOPATHIC PARKINSONS-DISEASE - A CLINICOPATHOLOGICAL STUDY OF 100 CASES [J].

HUGHES, AJ ;

DANIEL, SE ;

KILFORD, L ;

LEES, AJ .

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY, 1992, 55 (03) :181-184

[6] Meta-Analysis of Early Nonmotor Features and Risk Factors for Parkinson Disease [J].

Noyce, Alastair J. ;

Bestwick, Jonathan P. ;

Silveira-Moriyama, Laura ;

Hawkes, Christopher H. ;

Giovannoni, Gavin ;

Lees, Andrew J. ;

Schrag, Anette .

ANNALS OF NEUROLOGY, 2012, 72 (06) :893-901

[7]

Parkinson J., 1817, ESSAY SHAKING PALSY

[8] MDS clinical diagnostic criteria for Parkinson's disease [J].

Postuma, Ronald B. ;

Berg, Daniela ;

Stern, Matthew ;

Poewe, Werner ;

Olanow, C. Warren ;

Oertel, Wolfgang ;

Obeso, Jose ;

Marek, Kenneth ;

Litvan, Irene ;

Lang, Anthony E. ;

Halliday, Glenda ;

Goetz, Christopher G. ;

Gasser, Thomas ;

Dubois, Bruno ;

Chan, Piu ;

Bloem, Bastiaan R. ;

Adler, Charles H. ;

Deuschl, Guenther .

MOVEMENT DISORDERS, 2015, 30 (12) :1591-1599

[9] Non motor subtypes and Parkinson's disease [J].

Sauerbier, Anna ;

Jenner, Peter ;

Todorova, Antoniya ;

Chaudhuri, K. Ray .

PARKINSONISM & RELATED DISORDERS, 2016, 22 :S41-S46

[10] Prediagnostic presentations of Parkinson's disease in primary care: a case-control study [J].

Schrag, Anette ;

Horsfall, Laura ;

Walters, Kate ;

Noyce, Alastair ;

Petersen, Irene .

LANCET NEUROLOGY, 2015, 14 (01) :57-64

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