A novel solid-phase linker strategy for the side-chain anchoring of arginine:: an expeditious route to arginine 7-amido-4-methylcoumarins

被引：7
作者：
Beythien, J
Barthélémy, S
Schneeberger, P
White, PD
机构：
[1] Merck Biosci Ltd, Novabiochem, Nottingham NG9 2JR, England
[2] Merck Biosci AG, Novabiochem, CH-4448 Laufelfingen, Switzerland
来源：
TETRAHEDRON LETTERS | 2006年 / 47卷 / 18期
关键词：
D O I：
10.1016/j.tetlet.2006.03.019
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel linker strategy for the efficient side-chain anchoring of arginine is described. The utility of this approach was demonstrated by the facile synthesis of arginine-specific fluorogenic peptide substrates by standard Fmoc solid phase peptide synthesis methods. (c) 2006 Elsevier Ltd. All rights reserved.
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收藏
页码：3009 / 3012
页数：4
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