Key stages in mammary gland development - Molecular mechanisms involved in the formation of the embryonic mammary gland

被引：136

作者：

Hens, JR ^{[1
]}

Wysolmerski, JJ

机构：

[1] Yale Univ, Sch Med, Dept Internal Med, Sect Endocrinol & Metab, New Haven, CT 06510 USA

[2] Anlyan Ctr Med Res & Educ, New Haven, CT USA

来源：

BREAST CANCER RESEARCH | 2005年 / 7卷 / 05期

关键词：

D O I：

10.1186/bcr1306

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The development of the embryonic mammary gland involves communication between the epidermis and mesenchyme and is coordinated temporally and spatially by various signaling pathways. Although many more genes are likely to control mammary gland development, functional roles have been identified for Wnt, fibroblast growth factor, and parathyroid hormone-related protein signaling. This review describes what is known about the molecular mechanisms that regulate embryonic mammary gland development.

引用

页码：220 / 224

页数：5

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