Pathogenicity and genetic characterisation of a novel reassortant, highly pathogenic avian influenza (HPAI) H5N6 virus isolated in Korea, 2017

被引：24

作者：

Kim, Young-Il ^{[1
,2
]}

Si, Young-Jae ^{[1
,2
]}

Kwon, Hyeok-Il ^{[1
,2
]}

Kim, Eun-Ha ^{[1
,2
]}

Park, Su-Jin ^{[1
,2
]}

Robles, Norbert John ^{[1
,2
]}

Hiep Dinh Nguyen ^{[1
,2
]}

Yu, Min-Ah ^{[1
,2
]}

Yu, Kwang-Min ^{[1
,2
]}

Lee, Youn-Jeong ^{[3
]}

Lee, Myoung-Heon ^{[3
]}

Choi, Young Ki ^{[1
,2
]}

机构：

[1] Chungbuk Natl Univ, Coll Med, Cheongju, South Korea

[2] Chungbuk Natl Univ, Med Res Inst, Cheongju, South Korea

[3] Anim & Plant Quarantine Agcy, Avian Influenza Res & Diagnost Div, Gimcheon Si, Gyeongsangbuk D, South Korea

来源：

EUROSURVEILLANCE | 2018年 / 23卷 / 07期

关键词：

A(H5N8); BIRDS;

D O I：

10.2807/1560-7917.ES.2018.23.7.18-00045

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We investigated influenza A(H(5)N6) viruses from migratory birds in Chungnam and Gyeonggi Provinces, South Korea following a reported die-off of poultry in nearby provinces in November 2017. Genetic analysis and virulence studies in chickens and ducks identified our isolate from December 2017 as a novel highly pathogenic avian influenza virus. It resulted from reassortment between the highly virulent H(5)N8 strain from Korea with the N6 gene from a low-pathogenic H(3)N6 virus from the Netherlands.

引用

页码：8 / 15

页数：8

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