Axillary lymphadenectomy for breast cancer in elderly patients and fibrin glue

被引:25
作者
Docimo, Giovanni [1 ]
Limongelli, Paolo [1 ]
Conzo, Giovanni [1 ]
Gili, Simona [1 ]
Bosco, Alfonso [1 ]
Rizzuto, Antonia [2 ]
Amoroso, Vincenzo [1 ]
Marsico, Salvatore [1 ]
Leone, Nicola [1 ]
Esposito, Antonio [1 ]
Vitiello, Chiara [1 ]
Fei, Landino [1 ]
Parmeggiani, Domenico [1 ]
Docimo, Ludovico [1 ]
机构
[1] Univ Naples 2, Dept Surg, Div Gen Surg, I-80131 Naples, Italy
[2] Magna Grecia Univ, Dept Med & Surg Sci, Catanzaro, Italy
关键词
PROSPECTIVE RANDOMIZED-TRIAL; SEROMA FORMATION; RISK-FACTORS; CLINICAL-TRIAL; REDUCE SEROMA; DISSECTION; DRAINAGE; SURGERY; FUNDOPLICATION; ELECTROCAUTERY;
D O I
10.1186/1471-2482-13-S2-S8
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: Axillary lymphadenectomy or sentinel biopsy is integral part of breast cancer treatment, yet seroma formation occurs in 15-85% of cases. Among methods employed to reduce seroma magnitude and duration, fibrin glue has been proposed in numerous studies with controversial results. Methods: Thirty patients over 60 years underwent quadrantectomy or mastectomy with level I/II axillary lymphadenectomy; a suction drain was fitted in all patients. Fibrin glue spray were applied to the axillary fossa in 15 patients; the other 15 patients were treated with harmonic scalpel. Results: Suction drainage was removed between post-operative Days 3 and 4. Seroma magnitude and duration were not significant in patients receiving fibrin glue compared with the harmonic scalpel group. Conclusions: Use of fibrin glue does not always prevent seroma formation, but can reduce seroma magnitude, duration and necessary evacuative punctures.
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页数:5
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