A Bayesian network model for predicting pregnancy after in vitro fertilization

被引:31
作者
Corani, G. [1 ]
Magli, C. [2 ]
Giusti, A. [1 ]
Gianaroli, L. [2 ]
Garnbardella, L. M. [1 ]
机构
[1] Ist Dalle Molle Studi Intelligenza Artificiale ID, Manno, Switzerland
[2] Int Inst Reprod Med IIRM, Lugano, Switzerland
基金
瑞士国家科学基金会;
关键词
In vitro fertilization (IVF); Bayesian networks; EM algorithm; MAP estimation; Classification; SINGLE EMBRYO-TRANSFER; MORPHOLOGY; SELECTION; BENEFITS; OUTCOMES; OOCYTE; ZYGOTE; RISKS; SCORE;
D O I
10.1016/j.compbiomed.2013.07.035
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
We present a Bayesian network model for predicting the outcome of in vitro fertilization (IVF). The problem is characterized by a particular missingness process; we propose a simple but effective averaging approach which improves parameter estimates compared to the traditional MAP estimation. We present results with generated data and the analysis of a real data set. Moreover, we assess by means of a simulation study the effectiveness of the model in supporting the selection of the embryos to be transferred. (C) 2013 Elsevier Ltd. All rights reserved.
引用
收藏
页码:1783 / 1792
页数:10
相关论文
共 35 条
[1]  
Alpha Scientists in Reproductive Medicine and ESHRE Special Interest Group of Embryology, 2011, Hum Reprod, V26, P1270, DOI 10.1093/humrep/der037
[2]  
[Anonymous], 2002, MODELING MED DECISIO
[3]  
[Anonymous], 2006, Introduction to Data Mining
[4]  
[Anonymous], 2021, Bayesian data analysis
[5]  
[Anonymous], INT JOINT C ART INT
[6]  
[Anonymous], 2000, NIPS
[7]   The use of the area under the roc curve in the evaluation of machine learning algorithms [J].
Bradley, AP .
PATTERN RECOGNITION, 1997, 30 (07) :1145-1159
[8]   Evaluation of day one embryo quality and IVF outcome - a comparison of two scoring systems [J].
Brezinova, Jana ;
Oborna, Ivana ;
Svobodova, Magda ;
Fingerova, Helena .
REPRODUCTIVE BIOLOGY AND ENDOCRINOLOGY, 2009, 7
[9]  
Corani G, 2012, P 6 EUR WORKSH PROB, P75
[10]   High outcome predictability after IVF using a combined score for zygote and embryo morphology and growth rate [J].
De Placido, G ;
Wilding, M ;
Strina, I ;
Alviggi, E ;
Alviggi, C ;
Mollo, A ;
Varicchio, MT ;
Tolino, A ;
Schiattarella, C ;
Dale, B .
HUMAN REPRODUCTION, 2002, 17 (09) :2402-2409