Drugs as P-glycoprotein substrates, inhibitors, and inducers

被引：297
作者：
Kim, RB
机构：
[1] Vanderbilt Univ, Sch Med, Dept Med, Div Clin Pharmacol, Nashville, TN 37232 USA
[2] Vanderbilt Univ, Sch Med, Dept Pharmacol, Div Clin Pharmacol, Nashville, TN 37232 USA
来源：
DRUG METABOLISM REVIEWS | 2002年 / 34卷 / 1-2期
关键词：
D O I：
10.1081/DMR-120001389
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
[No abstract available]
引用
收藏
页码：47 / 54
页数：8
相关论文
共 57 条
[1]   Biochemical, cellular, and pharmacological aspects of the multidrug transporter [J].
Ambudkar, SV ;
Dey, S ;
Hrycyna, CA ;
Ramachandra, M ;
Pastan, I ;
Gottesman, MM .
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 1999, 39 :361-398
[2]  
Aquilante CL, 1999, LIFE SCI, V66, pPL47
[3]   Steroid transport, accumulation, and antagonism of P-glycoprotein in multidrug-resistant cells [J].
Barnes, KM ;
Dickstein, B ;
Cutler, GB ;
Fojo, T ;
Bates, SE .
BIOCHEMISTRY, 1996, 35 (15) :4820-4827
[4]   Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein-mediated secretion [J].
Boyd, RA ;
Stern, RH ;
Stewart, BH ;
Wu, XC ;
Reyner, EL ;
Zegarac, EA ;
Randinitis, EJ ;
Whitfield, L .
JOURNAL OF CLINICAL PHARMACOLOGY, 2000, 40 (01) :91-98
[5]  
CALLAGHAN R, 1993, J BIOL CHEM, V268, P16059
[6]  
Choo EF, 2000, DRUG METAB DISPOS, V28, P655
[7]  
Chu XY, 1999, DRUG METAB DISPOS, V27, P440
[8]  
Collett A, 1999, J PHARMACOL EXP THER, V288, P171
[9]   Secretion of sparfloxacin from the human intestinal Caco-2 cell line is altered by P-glycoprotein inhibitors [J].
Cormet-Boyaka, E ;
Huneau, JF ;
Mordrelle, A ;
Boyaka, PN ;
Carbon, C ;
Rubinstein, E ;
Tomé, T .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1998, 42 (10) :2607-2611
[10]  
Cvetkovic M, 1999, DRUG METAB DISPOS, V27, P866
123456