Correlation between reduced daptomycin susceptibility and vancomycin resistance in vancomycin-intermediate Staphylococcus aureus

被引：324
作者：
Cui, LZ
Tominaga, E
Neoh, HM
Hiramatsu, K
机构：
[1] Juntendo Univ, Fac Med, Dept Bacteriol, Bunkyo Ku, Tokyo 1138421, Japan
[2] Juntendo Univ, Fac Med, Dept Infect Control Sci, Bunkyo Ku, Tokyo 1138421, Japan
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2006年 / 50卷 / 03期
关键词：
D O I：
10.1128/AAC.50.3.1079-1082.2006
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
We present here findings of a strong positive correlation between reduced daptomycin susceptibility and vancomycin resistance in vancomycin-intermediate Staphylococcus aureus (VISA). This correlation is related to cell wall thickening, suggesting that, similar to the case with vancomycin resistance in VISA, the physical barrier of a thickened cell wall may contribute to daptomycin resistance in S. aureus.
引用
收藏
页码：1079 / 1082
页数：4
相关论文
共 20 条
  • [1] In vitro activities of daptomycin, arbekacin, vancomycin, and gentamicin alone and/or in combination against glycopeptide intermediate-resistant Staphylococcus aureus in an infection model
    Akins, RL
    Rybak, MJ
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (07) : 1925 - 1929
  • [2] Bactericidal activities of two daptomycin regimens against clinical strains of glycopeptide intermediate-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium, and methicillin-resistant Staphylococcus aureus isolates in an in vitro pharmacodynamic model with simulated endocardial vegetations
    Akins, RL
    Rybak, MJ
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2001, 45 (02) : 454 - 459
  • [3] Daptomycin, a new drug class for the treatment of gram-positive infections
    Alder, JD
    [J]. DRUGS OF TODAY, 2005, 41 (02) : 81 - 90
  • [4] Vancomycin-resistant enterococci
    Cetinkaya, Y
    Falk, P
    Mayhall, CG
    [J]. CLINICAL MICROBIOLOGY REVIEWS, 2000, 13 (04) : 686 - +
  • [5] Daptomycin dose-effect relationship against resistant gram-positive organisms
    Cha, R
    Grucz, RG
    Rybak, MJ
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (05) : 1598 - 1603
  • [6] Cell wall thickening is a common feature of vancomycin resistance in Staphylococcus aureus
    Cui, L
    Ma, XX
    Sato, K
    Okuma, K
    Tenover, FC
    Mamizuka, EM
    Gemmell, CG
    Kim, MN
    Ploy, MC
    El Solh, N
    Ferraz, V
    Hiramatsu, K
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (01) : 5 - 14
  • [7] Cui Longzhu, 2003, P187
  • [8] Novel mechanism of antibiotic resistance originating in vancomycin-intermediate Staphylococcus aureus
    Cui, LZ
    Iwamoto, A
    Lian, JQ
    Neoh, HM
    Maruyama, T
    Horikawa, Y
    Hiramatsu, K
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2006, 50 (02) : 428 - 438
  • [9] DNA microarray-based identification of genes associated with glycopeptide resistance in Staphylococcus aureus
    Cui, LZ
    Lian, JQ
    Neoh, HM
    Reyes, E
    Hiramatsu, K
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (08) : 3404 - 3413
  • [10] Contribution of a thickened cell wall and its glutamine nonamidated component to the vancomycin resistance expressed by Staphylococcus aureus Mu50
    Cui, LZ
    Murakami, H
    Kuwahara-Arai, K
    Hanaki, H
    Hiramatsu, K
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (09) : 2276 - 2285
12