New supports for solid-phase organic synthesis: development of polystyrene resins containing tetrahydrofuran derived cross-linkers

被引：132
作者：
Toy, PH
Janda, KD
机构：
[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA
[2] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 35期
基金：
美国国家卫生研究院;
关键词：
solid-phase synthesis; polymer support; resins;
D O I：
10.1016/S0040-4039(99)01251-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Polystyrene resins containing flexible tetrahydrofuran derived cross-linkers are presented. These cross-linkers were designed to render the resins more 'organic solvent-like' and thus impart increased swelling/solvation characteristics in the resins with regard to common solvents used in solid-phase organic synthesis. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：6329 / 6332
页数：4
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