Discovery of metformin derivatives with potent antitumor activity in triple-negative breast cancer

被引:0
|
作者
Marquez-Garban, D. C. [1 ]
Deng, G. [1 ]
Anderson, N. [1 ]
Aivazyan, L. [1 ]
Kazmi, N. [1 ]
Hamilton, N. [1 ]
Jung, M. E. [1 ]
Pietras, R. J. [1 ]
机构
[1] Univ Calif Los Angeles, Los Angeles, CA USA
关键词
D O I
10.1158/0008-5472.SABCS12-PD03-04
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
PD03-04
引用
收藏
页数:1
相关论文
共 50 条
  • [1] Discovery of novel metformin derivatives with potent antitumor activity in combination with immunotherapy for treatment of triple-negative breast cancer
    Marquez-Garban, Diana C.
    Deng, Gang
    Comin-Anduix, Begonya
    Muhunthan, Vishaka
    Ma, Gaoyuan
    Murphy, Jennifer
    Garcia, Alejandro J.
    Yanes, Cristian D.
    Burton, Lorena R.
    Hamilton, Nalo
    Shackelford, David
    Jung, Michael E.
    Pietras, Richard J.
    CANCER RESEARCH, 2020, 80 (16)
  • [2] Discovery of Pyrimidinediamine Derivatives as Potent Methuosis Inducers for the Treatment of Triple-Negative Breast Cancer
    He, Jia
    Wang, Luzhen
    Mi, DaZhao
    Guan, Tian
    Liu, Wenjing
    He, Peng
    Gu, Haijun
    Li, Yuzhan
    Peng, Yangrui
    Jia, Ai-Qun
    Chen, Ceshi
    Chen, Yihua
    JOURNAL OF MEDICINAL CHEMISTRY, 2023, 66 (11) : 7421 - 7437
  • [3] Combinations of ciclopirox olamine and metformin exert synergistic antitumor activity in triple-negative breast cancer
    Wu, Yakun
    Lyu, Hui
    Tan, Congcong
    Larsen, Margaret E.
    Huang, Shile
    Liu, Bolin
    CANCER RESEARCH, 2024, 84 (06)
  • [4] Potent antitumor activity of cepharanthine against triple-negative breast cancer spheroids compared with tetrandrine
    Kiyomi, Anna
    Miyakawa, Risako
    Matsumoto, Juri
    Yamazaki, Kyousuke
    Imai, Shinobu
    Yuan, Bo
    Hirano, Toshihiko
    Sugiura, Munetoshi
    ONCOLOGY LETTERS, 2020, 20 (06)
  • [5] Antitumor activity of celecoxib with docetaxel on human triple-negative breast cancer cells
    Ajikanari, Oktay
    Miaadi, Elham
    Hedayat, Mohaddeseh
    Jafari, Reza
    Asghari, Rahim
    Zolbanin, Naime Majidi
    GENE REPORTS, 2025, 38
  • [6] Discovery of novel steroidal-chalcone hybrids with potent and selective activity against triple-negative breast cancer
    Hou, Qiangqiang
    Lin, Xin
    Lu, Xiang
    Bai, Chengfeng
    Wei, Hanlin
    Luo, Guoshun
    Xiang, Hua
    BIOORGANIC & MEDICINAL CHEMISTRY, 2020, 28 (23)
  • [7] New metformin analogues for the treatment of triple-negative breast cancer
    Diers, Emelyne
    Deng, Gang
    Marquez-Garban, Diana
    Pietras, Richard
    Jung, Michael
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 251
  • [8] Expanding the arsenal: Metformin for the treatment of triple-negative breast cancer?
    Jiralerspong, Sao
    Angulo, Ana M. Gonzalez
    Hung, Mien-Chie
    CELL CYCLE, 2009, 8 (17) : 2681 - 2681
  • [9] Discovery of a potent inhibitor of CREB-mediated gene transcription with growth inhibitory activity in triple-negative breast cancer
    Xiao, Xiangshu
    Xie, Fuchun
    Li, Bingbing
    Fan, Qiuhua
    Xue, Changhui
    Qian, David Z.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246
  • [10] Antitumor activity of the glutaminase inhibitor, CB-839, in triple-negative breast cancer
    Gross, M.
    Budczies, J.
    Demo, S.
    Janes, J.
    Lewis, E.
    Parlati, F.
    MacKinnon, A.
    Rodriguez, M.
    Yang, J.
    Zhao, F.
    Richardson, A.
    Denkert, C.
    Fiehn, O.
    Bennett, M.
    CANCER RESEARCH, 2013, 73