Pomegranate juice as a functional food: a comprehensive review of its polyphenols, therapeutic merits, and recent patents

被引:4
作者
Fahmy, Heba [1 ]
Hegazi, Nesrine [2 ]
El-Shamy, Sherine [1 ]
Farag, Mohamed A. [3 ,4 ]
机构
[1] Modern Univ Technol & Informat, Fac Pharm, Pharmacognosy Dept, Cairo, Egypt
[2] Natl Res Ctr, Phytochem & Plant Systemat Dept, Div Pharmaceut Ind, POB 12622, Cairo, Egypt
[3] Cairo Univ, Dept Pharmacognosy, Fac Pharm, Cairo 11562, Egypt
[4] Amer Univ Cairo, Sch Sci & Engn, Chem Dept, New Cairo, Egypt
关键词
PUNICA-GRANATUM L; NITRIC-OXIDE SYNTHASE; ANTIOXIDANT ACTIVITY; PHENOLIC-COMPOUNDS; PROSTATE-CANCER; BLOOD-PRESSURE; DOUBLE-BLIND; FRUIT; CONSUMPTION; CULTIVARS;
D O I
10.1039/d0fo01251c
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Pomegranate (Punica granatum) is an ancient perennial plant species of thePunicaceaefamily and is regarded as the 'miracle fruit' for its seeds being consumed as food, juice and as a functional food. Significant modern pharmacological and clinical evidence has highlighted the wide medicinal applications of pomegranate fruit parts and its juice. Pomegranate juice (PJ) that is superior to other fruit juices is a fortified source of dietary polyphenols with potential antioxidant capacity. Polyphenols of PJ include tannins, anthocyanins, and flavonoids. The presence of these beneficial phytochemicals is directly linked to its favourable health benefitsviz., obesity and diabetes management and anti-inflammatory effects. This comprehensive review capitalizes on PJ with emphasis on the interrelationship between its holistic chemical composition, metabolism and biological effects. Moreover, the review recapitulates on the diverse health benefits of PJ and related patents in the field of PJ production to ensure the best produced juice quality.
引用
收藏
页码:5768 / 5781
页数:14
相关论文
共 94 条
[1]  
Ahmadiankia N, 2019, IRAN J BASIC MED SCI, V22, P977, DOI 10.22038/ijbms.2019.34653.8217
[2]   Pomegranate peel and peel extracts: Chemistry and food features [J].
Akhtar, Saeed ;
Ismail, Tariq ;
Fraternale, Daniele ;
Sestili, Piero .
FOOD CHEMISTRY, 2015, 174 :417-425
[3]   Pomegranate (Punica granatum) Juice Shows Antioxidant Activity against Cutaneous Leishmaniasis-Induced Oxidative Stress in Female BALB/c Mice [J].
Alkathiri, Badriah ;
El-Khadragy, Manal F. ;
Metwally, Dina M. ;
Al-Olayan, Ebtesam M. ;
Bakhrebah, Muhammed A. ;
Moneim, Ahmed E. Abdel .
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2017, 14 (12)
[4]   Pomegranate as a Possible Treatment in Reducing Risk of Developing Wound Healing, Obesity, Neurodegenerative Disorders, and Diabetes Mellitus [J].
AlMatar, Manaf ;
Islam, Md Rashedul ;
Albarri, Osman ;
Var, Isil ;
Kokal, Fatih .
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2018, 18 (06) :507-526
[5]  
Anderson S., 2014, US pat., Patent No. [US2014/0242164 A1, 20140242164]
[6]  
[Anonymous], 2011, CELL DEATH DIS
[7]  
[Anonymous], 2018, VOX 0919
[8]  
Asgary S, 2013, ARYA ATHEROSCLER, V9, P326
[9]  
Baban B. C., 2017, US pat., Patent No. [US2017/0252388A1, 20170252388]
[10]   Fresh pomegranate juice ameliorates insulin resistance, enhances β-cell function, and decreases fasting serum glucose in type 2 diabetic patients [J].
Banihani, S. A. ;
Makahleh, S. M. ;
El-Akawi, Z. ;
Al-Fashtaki, R. A. ;
Khabour, O. F. ;
Gharibeh, M. Y. ;
Saadah, N. A. ;
Al-Hashimi, F. H. ;
Al-Khasieb, N. J. .
NUTRITION RESEARCH, 2014, 34 (10) :862-867