Deep learning for detection and segmentation of artefact and disease instances in gastrointestinal endoscopy ?

被引:98
作者
Ali, Sharib [1 ,2 ,4 ]
Dmitrieva, Mariia [1 ,2 ]
Ghatwary, Noha [8 ]
Bano, Sophia [9 ,10 ]
Polat, Gorkem [12 ]
Temizel, Alptekin [12 ]
Krenzer, Adrian [13 ]
Hekalo, Amar [13 ]
Guo, Yun Bo [14 ]
Matuszewski, Bogdan [14 ]
Gridach, Mourad [26 ]
Voiculescu, Irina [15 ]
Yoganand, Vishnusai [16 ]
Chavan, Arnav [17 ]
Raj, Aryan [17 ]
Nguyen, Nhan T. [18 ]
Tran, Dat Q. [18 ]
Huynh, Le Duy [19 ]
Boutry, Nicolas [19 ]
Rezvy, Shahadate [20 ]
Chen, Haijian [21 ]
Choi, Yoon Ho [22 ]
Subramanian, Anand [23 ]
Balasubramanian, Velmurugan [24 ]
Gao, Xiaohong W. [20 ]
Hu, Hongyu [25 ]
Liao, Yusheng [25 ]
Stoyanov, Danail [9 ,10 ]
Daul, Christian [11 ]
Realdon, Stefano [6 ]
Cannizzaro, Renato [7 ]
Lamarque, Dominique [5 ]
Tran-Nguyen, Terry [3 ]
Bailey, Adam [3 ,4 ]
Braden, Barbara [3 ,4 ]
East, James E. [3 ,4 ]
Rittscher, Jens [1 ,2 ]
机构
[1] Univ Oxford, Inst Biomed Engn, Old Rd Campus, Oxford, England
[2] Univ Oxford, Big Data Inst, Old Rd Campus, Oxford, England
[3] Univ Oxford, John Radcliffe Hosp, Expt Med Div, Translat Gastroenterol Unit, Oxford, England
[4] Oxford NIHR Biomed Res Ctr, Oxford, England
[5] Univ Versailles St Quentin en Yvelines, Hop Ambroise Pare, Versailles, France
[6] Inst Onclol Veneto, IOV IRCCS, Padua, Italy
[7] CRO Ctr Riferimento Oncol IRCCS, Aviano, Italy
[8] Arab Acad Sci & Technol, Comp Engn Dept, Alexandria, Egypt
[9] UCL, Wellcome EPSRC Ctr Intervent & Surg Sci WEISS, London, England
[10] UCL, Dept Comp Sci, London, England
[11] Univ Lorraine, CNRS, CRAN UMR 7039, Nancy, France
[12] Middle East Tech Univ, Grad Sch Informat, Ankara, Turkey
[13] Univ Wurzburg, Dept Artificial Intelligence & Knowledge Syst, Wurzburg, Germany
[14] Univ Cent Lancashire, Sch Engn, Preston, Lancs, England
[15] Univ Oxford, Dept Comp Sci, Oxford, England
[16] Mimyk Med Simulat Pvt Ltd, Indian Inst Sci, Bengaluru, India
[17] Indian Inst Technol ISM, Dhanbad, Bihar, India
[18] Vingrp Big Data Inst VinBDI, Med Imaging Dept, Hanoi, Vietnam
[19] EPITA Res & Dev Lab LRDE, F-94270 Le Kremlin Bicetre, France
[20] Middlesex Univ London, Sch Sci & Technol, London, England
[21] Xiamen Univ, Sch Informat, Dept Comp Sci, Xiamen, Peoples R China
[22] Sungkyunkwan Univ, Samsung Adv Inst Hlth Sci & Tech SAIHST, Dept Hlth Sci & Tech, Seoul, South Korea
[23] Claritr India Pvt Ltd, Chennai, Tamil Nadu, India
[24] Indian Inst Technol, Sch Med Sci & Technol, Kharagpur, W Bengal, India
[25] Shanghai Jiao Tong Univ, Shanghai, Peoples R China
[26] Ibn Zohr Univ, Comp Sci HIT, Agadir, Morocco
基金
英国工程与自然科学研究理事会;
关键词
Endoscopy; Challenge; Artefact; Disease; Detection; Segmentation; Gastroenterology; Deep learning; VALIDATION; DIAGNOSIS;
D O I
10.1016/j.media.2021.102002
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
The Endoscopy Computer Vision Challenge (EndoCV) is a crowd-sourcing initiative to address eminent problems in developing reliable computer aided detection and diagnosis endoscopy systems and suggest a pathway for clinical translation of technologies. Whilst endoscopy is a widely used diagnostic and treatment tool for hollow-organs, there are several core challenges often faced by endoscopists, mainly: 1) presence of multi-class artefacts that hinder their visual interpretation, and 2) difficulty in identifying subtle precancerous precursors and cancer abnormalities. Artefacts often affect the robustness of deep learning methods applied to the gastrointestinal tract organs as they can be confused with tissue of interest. EndoCV2020 challenges are designed to address research questions in these remits. In this paper, we present a summary of methods developed by the top 17 teams and provide an objective comparison of state-of-the-art methods and methods designed by the participants for two sub-challenges: i) artefact detection and segmentation (EAD2020), and ii) disease detection and segmentation (EDD2020). Multi-center, multi-organ, multi-class, and multi-modal clinical endoscopy datasets were compiled for both EAD2020 and EDD2020 sub-challenges. The out-of-sample generalization ability of detection algorithms was also evaluated. Whilst most teams focused on accuracy improvements, only a few methods hold credibility for clinical usability. The best performing teams provided solutions to tackle class imbalance, and variabilities in size, origin, modality and occurrences by exploring data augmentation, data fusion, and optimal class thresholding techniques. (c) 2021 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY-NC-ND license ( http://creativecommons.org/licenses/by-nc-nd/4.0/ )
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页数:24
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