A Novel Genotype of Leptospira interrogans Recovered from Leptospirosis Outbreak Samples from Southern Thailand

被引:6
作者
Thongdee, Metawee [1 ]
Chaiwattanarungruengpaisan, Somjit [1 ]
Lekcharoen, Paisin [1 ]
Yimchoho, Nirandorn [3 ]
Buathong, Rome [3 ]
Wiriyarat, Witthawat [1 ,2 ]
机构
[1] Mahidol Univ, Monitoring & Surveillance Ctr Zoonot Dis Wildlife, Fac Vet Sci, Salaya 73170, Nakhon Pathom, Thailand
[2] Mahidol Univ, Dept Preclin & Appl Anim Sci, Fac Vet Sci, Bangkok, Thailand
[3] Minist Publ Hlth, Dept Dis Control, Bur Epidemiol, Mueang Nonthaburi, Nonthaburi, Thailand
关键词
WOLFFII;
D O I
10.7883/yoken.JJID.2019.061
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
We performed Leptospira culture analysis of 76 clinical samples collected from animals and of six soil samples for the investigation of a leptospirosis outbreak in southern Thailand in 2017. Leptospires were recovered from a kidney sample (a fatal canine leptospirosis case) and from all the soil samples. Next, 16S rRNA sequence analysis demonstrated that the clinical isolate was closely related to the pathogenic L. interrogans, whereas the soil isolates represented different species, including pathogenic L. ellisii, intermediate L. wolffii, and nonpathogenic L. yanagawae. Multilocus sequence typing identified an isolate of L. interrogans as a novel sequence type (ST263), suggesting that the causative agent of the canine leptospirosis in the southern Thailand outbreak has a unique genetic profile.
引用
收藏
页码:343 / 346
页数:4
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