Autophagy, Apoptosis, and the Influenza Virus M2 Protein

被引：62
|
作者：
Rossman, Jeremy S. [1 ,2 ]
Lamb, Robert A. [1 ,2 ]
机构：
[1] Northwestern Univ, Dept Biochem Mol Biol & Cell Biol, Evanston, IL 60208 USA
[2] Northwestern Univ, Howard Hughes Med Inst, Evanston, IL 60208 USA
来源：
CELL HOST & MICROBE | 2009年 / 6卷 / 04期
关键词：
REPLICATION;
D O I：
10.1016/j.chom.2009.09.009
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Viral subversion and inhibition of host cell autophagy has been documented for several viruses. In this issue of Cell Host & Microbe, Gannage et al. (2009) show that the influenza virus M2 integral membrane protein blocks autophagosome maturation, significantly affecting host cell apoptosis.
引用
收藏
页码：299 / 300
页数：2
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