Alpha-synuclein and presynaptic function - Implications for Parkinson's disease

被引:27
|
作者
Lykkebo, S [1 ]
Jensen, PH [1 ]
机构
[1] Aarhus Univ, Dept Biochem Med, DK-8000 Aarhus C, Denmark
关键词
synuclein; synapse; axon; vesicles; Parkinson's disease; Lewy body;
D O I
10.1385/NMM:2:2:115
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
This article focuses on alpha-synuclein's role in normal and pathological axonal and presynaptic functions and its relationship to Parkinson's disease. It is not possible to mention all the contributions to aspects of this area. Readers interested in alpha-synuclein's relation to aggregation, Lewy lesions, and pathological modifications are referred to the many reviews (see Goldberg and Lansbury 2000; Galvin 2001a; Goedert 2001).
引用
收藏
页码:115 / 129
页数:15
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