A label-free ratiometric electrochemical DNA sensor for monitoring intracellular redox homeostasis

被引:38
|
作者
Liu, Xinping [1 ,2 ,3 ]
Yan, Zhengqing [1 ,2 ,4 ]
Sun, Yuhuan [1 ,2 ,3 ]
Ren, Jinsong [1 ,2 ]
Qu, Xiaogang [1 ,2 ]
机构
[1] Chinese Acad Sci, Changchun Inst Appl Chem, Biol Chem Lab, Changchun 130022, Jilin, Peoples R China
[2] Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Rare Earth Resource Utilizat, Changchun 130022, Jilin, Peoples R China
[3] Univ Sci & Technol China, Hefei 230029, Anhui, Peoples R China
[4] Univ Chinese Acad Sci, Beijing 100039, Peoples R China
关键词
HYBRIDIZATION CHAIN-REACTION; TURN-ON DETECTION; SELECTIVE DETECTION; ALZHEIMERS-DISEASE; GRAPHENE OXIDE; L-CYSTEINE; SIGNAL-ON; GLUTATHIONE; FLUORESCENT; THIOLS;
D O I
10.1039/c7cc03239k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A label-free ratiometric electrochemical biosensor was constructed for monitoring intracellular redox homeostasis by DNA metallization-mediated hybridization chain reaction amplification. This platform could also be used to discriminate cancer cells and normal cells.
引用
收藏
页码:6215 / 6218
页数:4
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