Chaetomium-like fungi causing opportunistic infections in humans: a possible role for extremotolerance

被引：31

作者：

Ahmed, Sarah A. ^{[1
,2
,3
]}

Khan, Ziauddin ^{[4
]}

Wang, Xue-wei ^{[2
,5
]}

Moussa, Tarek A. A. ^{[6
,7
]}

Al-Zahrani, Hassan S. ^{[6
]}

Almaghrabi, Omar A. ^{[6
]}

Sutton, Deanna A. ^{[8
]}

Ahmad, S.

Groenewald, Johannes Z. ^{[2
]}

Alastruey-Izquierdo, A. ^{[9
]}

van Diepeningen, Anne ^{[2
]}

Menken, S. B. J. ^{[3
]}

Najafzadeh, M. J. ^{[10
]}

Crous, Pedro W. ^{[2
]}

Cornely, Oliver ^{[11
]}

Hamprecht, Axel ^{[12
]}

Vehreschild, Maria J. G. T. ^{[11
]}

Kindo, A. J. ^{[13
]}

de Hoog, G. Sybren ^{[2
,3
,6
,14
,15
,16
,17
]}

机构：

[1] Univ Khartoum, Fac Med Lab Sci, Khartoum, Sudan

[2] CBS KNAW Fungal Biodivers Ctr, NL-3508 AD Utrecht, Netherlands

[3] Univ Amsterdam, Inst Biodivers & Ecosyst Dynam, Amsterdam, Netherlands

[4] Kuwait Univ, Fac Med, Dept Microbiol, Kuwait, Kuwait

[5] Chinese Acad Sci, Inst Microbiol, State Key Lab Mycol, Beijing, Peoples R China

[6] King Abdulaziz Univ, Fac Sci, Dept Biol Sci, Jeddah 21413, Saudi Arabia

[7] Cairo Univ, Fac Sci, Dept Bot & Microbiol, Giza, Egypt

[8] Univ Texas Hlth Sci Ctr San Antonio, Dept Pathol, Fungus Testing Lab, San Antonio, TX 78229 USA

[9] Inst Salud Carlos III, Natl Ctr Microbiol, Mycol Reference Lab, Microbiol Serv, Madrid, Spain

[10] Mashhad Univ Med Sci, Dept Parasitol & Mycol, Mashhad, Iran

[11] Univ Hosp Cologne, Dept Internal Med 1, German Ctr Infect Res DZIF Cologne Bonn, Cologne, Germany

[12] Univ Cologne, Inst Med Microbiol Immunol & Hyg, D-50931 Cologne, Germany

[13] Sri Ramachandra Univ, Dept Microbiol, Madras, Tamil Nadu, India

[14] Peking Univ, Hlth Sci Ctr, Res Ctr Med Mycol, Beijing 100871, Peoples R China

[15] Sun Yat Sen Univ, Sun Yat Sen Mem Hosp, Guangzhou 510275, Guangdong, Peoples R China

[16] Second Mil Med Univ, Changzheng Hosp, Shanghai Inst Med Mycol, Shanghai, Peoples R China

[17] Univ Fed Parana, Basic Pathol Dept, Curitiba, Parana, Brazil

来源：

FUNGAL DIVERSITY | 2016年 / 76卷 / 01期

关键词：

PHEOHYPHOMYCOSIS; SUBRAMANIULA; PAPULASPORA; DNA; IDENTIFICATION; ACHAETOMIUM; MADURELLA; AGENT; TOOL;

D O I：

10.1007/s13225-015-0338-5

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Members of the family Chaetomiaceae are ubiquitous ascosporulating fungi commonly, which reside in soil enriched with manure or cellulosic materials. Their role as human pathogens is largely ignored. However, the ability of some species to grow at high temperature enables them to play an important role as opportunistic pathogens. The family contains several genera and species that have never been reported to cause human infection. Hereby, three new species are described; two belong to the genus Subramaniula and one represents a Chaetomium species. Subramaniula asteroides was isolated from various sources including eye and skin infections as well as from the natural environment, and S. obscura was isolated from a toe infection. Chaetomium anamorphosum was isolated from a kidney transplant patient suffering from fungal peritonitis. All species described were previously misidentified as Papulaspora spp. due to the formation of cellular clumps or bulbil-like structures, which are characteristic of Papulaspora. The isolates failed to form sexual fruit bodies and ascospores remained absent, which is an unusual feature for the generally ascosporulating genera Chaetomium and Subramaniula; minute conidia from phialides were sometimes observed.

引用

页码：11 / 26

页数：16

共 53 条

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