Laser-tissue interaction modeling with LATIS

被引：49

作者：

London, RA ^{[1
]}

Glinsky, ME ^{[1
]}

Zimmerman, GB ^{[1
]}

Bailey, DS ^{[1
]}

Eder, DC ^{[1
]}

Jacques, SL ^{[1
]}

机构：

[1] OREGON MED LASER CTR,PROVIDENCE ST VINCENT MED CTR,PORTLAND,OR 97225

来源：

APPLIED OPTICS | 1997年 / 36卷 / 34期

关键词：

laser-tissue modeling; dynamic optics; laser dosimetry; tissue damage;

D O I：

10.1364/AO.36.009068

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

The role of modeling in designing new treatment protocols and instruments is discussed. A computer program for modeling laser-tissue interaction named LATIS is described. Interactions are divided into the processes of laser propagation, thermal effects, material effects, and hydrodynamics. Full coupling of the processes is taken into consideration. Applications in photothermal and photomechanical laser-tissue interactions are briefly discussed. A detailed description is given of a particular application of LATIS to study the effects of dynamic optical properties on dosimetry in photothermal therapy. Optical properties are functions of tissue damage, as determined by previous measurements. Results are presented for the time variation of the light distribution and damage within the tissue as the optical properties of the tissue are altered. It is found that proper accounting of dynamical optical properties is important for accurate dosimetry modeling. (C) 1997 Optical Society of America.

引用

页码：9068 / 9074

页数：7

共 25 条

[1]

ALLEY WE, 1992, UCRLLR10582092, P160

[2]

[Anonymous], 1984, NBS/NRC Steam Tables: Thermodynamic and Transport Properties and Computer Programs for Vapor and Liquid States of Water in SI Units

[3]

Cho Y.I., 1992, ADV HEAT TRANSFER, V22

[4]

CILESIZ I, 1995, P SOC PHOTO-OPT INS, V2395, P523, DOI 10.1117/12.209141

[5]

Dubois P. F., 1994, Computers in Physics, V8, P70

[6]

GLENN TN, 1994, P SOC PHOTO-OPT INS, V2134, P383

[7]

Glinsky Michael E., 1996, Proceedings of the SPIE - The International Society for Optical Engineering, V2623, P349, DOI 10.1117/12.230347

[8]

GLINSKY ME, 1995, P SOC PHOTO-OPT INS, V2391, P262, DOI 10.1117/12.209891

[9] Diffuse radiation in the galaxy [J].

Henyey, LG ;

Greenstein, JL .

ASTROPHYSICAL JOURNAL, 1941, 93 (01) :70-83

[10]

Jacques S. L., 1987, Lasers in the Life Sciences, V1, P309

← 1 2 3 →