Modulating the tumor microenvironment to enhance efficacy of PARP inhibitors

被引:1
|
作者
Mehibel, Manal
Xu, Jimmy
Diep, Anh
Thakkar, Kaushik
Li, Caiyun G.
Xiao, Yiren
Rankin, Erinn
Giaccia, Amato
机构
[1] Stanford Univ, Stanford, CA 94305 USA
[2] Stanford Sch Med, Stanford, CA 94305 USA
关键词
D O I
10.1200/JCO.2019.37.15_suppl.e14715
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
e14715
引用
收藏
页数:1
相关论文
共 50 条
  • [1] Modulating the Tumor Microenvironment to Enhance Tumor Nanomedicine Delivery
    Zhang, Bo
    Hu, Yu
    Pang, Zhiqing
    FRONTIERS IN PHARMACOLOGY, 2017, 8
  • [2] Combining Tumor Microenvironment Modulating Nanoparticles with Doxorubicin to Enhance Chemotherapeutic Efficacy and Boost Antitumor Immunity
    Amini, Mohammad Ali
    Abbasi, Azhar Z.
    Cai, Ping
    Lip, Hoyin
    Gordijo, Claudia R.
    Li, Jason
    Chen, Branson
    Zhang, Li
    Rauth, Andrew M.
    Wu, Xiao Yu
    JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2019, 111 (04): : 399 - 408
  • [3] Modulating the tumor microenvironment to enhance cancer immunotherapy by inducing phosphatidylserine expression on the tumor surface
    Kaneko, Kensuke
    Osada, Takuya
    Freimark, Bruce D.
    Lyerly, Herbert Kim
    CANCER IMMUNOLOGY RESEARCH, 2017, 5 (03)
  • [4] Boosting antitumor efficacy of nanoparticles by modulating tumor mechanical microenvironment
    Zhang, Xiaoqiong
    Zhang, Xiaojuan
    Yong, Tuying
    Gan, Lu
    Yang, Xiangliang
    EBIOMEDICINE, 2024, 105
  • [5] mTOR Inhibitors Can Enhance the Anti-Tumor Effects of DNA Vaccines through Modulating Dendritic Cell Function in the Tumor Microenvironment
    Chen, Yu-Li
    Lin, Han-Wei
    Sun, Nai-Yun
    Yie, Jr-Chi
    Hung, Hsueh-Chih
    Chen, Chi-An
    Sun, Wei-Zen
    Cheng, Wen-Fang
    CANCERS, 2019, 11 (05)
  • [6] Targeting cancer stem cells in the tumor microenvironment: An emerging role of PARP inhibitors
    Paul, Subarno
    Sinha, Saptarshi
    Kundu, Chanakya Nath
    PHARMACOLOGICAL RESEARCH, 2022, 184
  • [7] The role of cisplatin in modulating the tumor immune microenvironment and its combination therapy strategies: a new approach to enhance anti-tumor efficacy
    Li, Guandu
    Che, Xiangyu
    Wang, Shijin
    Liu, Dequan
    Xie, Deqian
    Jiang, Bowen
    Zheng, Zunwen
    Zheng, Xu
    Wu, Guangzhen
    ANNALS OF MEDICINE, 2025, 57 (01)
  • [8] FANCI Inhibition Induces PARP1 Redistribution to Enhance the Efficacy of PARP Inhibitors in Breast Cancer
    Huang, Yu-Zhou
    Sang, Ming-Yi
    Xi, Pei-Wen
    Xu, Ruo-Xi
    Cai, Meng-Yuan
    Wang, Zi-Wen
    Zhao, Jian-Yi
    Li, Yi-Han
    Wei, Ji-Fu
    Ding, Qiang
    CANCER RESEARCH, 2024, 84 (20) : 3447 - 3463
  • [9] Ceralasertib enhance efficacy of anti-PDL1 treatment by modulating the tumor microenvironment in a IFNAR I dependent manner
    Sanseviero, Emilio
    Taylor, Devon
    Tohumeken, Sehmus
    Mai, Mimi
    Mostafa, Ali
    Milo, Marta
    Mulgrew, Kathy
    Fuchs, Serge
    Lau, Alan
    Barry, Simon
    Cobbold, Mark
    Gabrilovich, Dmitry
    CANCER IMMUNOLOGY RESEARCH, 2024, 12 (10)
  • [10] A synergistic approach for modulating the tumor microenvironment to enhance nano-immunotherapy in sarcomas
    Mpekris, Fotios
    Panagi, Myrofora
    Charalambous, Antonia
    Voutouri, Chrysovalantis
    Michael, Christina
    Papoui, Antonia
    Stylianopoulos, Triantafyllos
    NEOPLASIA, 2024, 51