Brain connectivity dynamics during social interaction reflect social network structure

被引:94
作者
Schmlazle, Ralf [1 ,2 ]
O'Donnell, Matthew Brook [2 ]
Garcia, Javier O. [3 ]
Cascio, Christopher N. [2 ]
Bayer, Joseph [4 ]
Bassett, Danielle S. [5 ,6 ]
Vettel, Jean M. [3 ,5 ,7 ]
Falk, Emily B. [2 ]
机构
[1] Michigan State Univ, Dept Commun, E Lansing, MI 48824 USA
[2] Univ Penn, Annenberg Sch Commun, Philadelphia, PA 19104 USA
[3] US Army Res Lab, Human Res & Engn Directorate, Aberdeen Proving Ground, MD 21005 USA
[4] Ohio State Univ, Sch Commun, Columbus, OH 43210 USA
[5] Univ Penn, Dept Bioengn, Philadelphia, PA 19104 USA
[6] Univ Penn, Dept Elect & Syst Engn, Philadelphia, PA 19104 USA
[7] Univ Calif Santa Barbara, Dept Psychol & Brain Sci, Santa Barbara, CA 93106 USA
基金
美国国家科学基金会;
关键词
social exclusion; mentalizing; fMRI; functional connectivity; social networks; PREFRONTAL CORTEX; RECONFIGURATION; EXCLUSION; REJECTION; PERSONALITY; ACTIVATION; EMERGENCE; STRENGTH; MODELS; HEALTH;
D O I
10.1073/pnas.1616130114
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Social ties are crucial for humans. Disruption of ties through social exclusion has a marked effect on our thoughts and feelings; however, such effects can be tempered by broader social network resources. Here, we use fMRI data acquired from 80 male adolescents to investigate how social exclusion modulates functional connectivity within and across brain networks involved in social pain and understanding the mental states of others (i.e., mentalizing). Furthermore, using objectively logged friendship network data, we examine how individual variability in brain reactivity to social exclusion relates to the density of participants' friendship networks, an important aspect of social network structure. We find increased connectivity within a set of regions previously identified as a mentalizing system during exclusion relative to inclusion. These results are consistent across the regions of interest as well as a whole-brain analysis. Next, examining how social network characteristics are associated with task-based connectivity dynamics, we find that participants who showed greater changes in connectivity within the mentalizing system when socially excluded by peers had less dense friendship networks. This work provides insight to understand how distributed brain systems respond to social and emotional challenges and how such brain dynamics might vary based on broader social network characteristics.
引用
收藏
页码:5153 / 5158
页数:6
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