Mucosa Associated Lymphoid Tissue (MALT) Lymphoma of the Thymus with Trisomy 18

被引:20
作者
Sunohara, Mitsuhiro [1 ]
Hara, Kei [1 ]
Osamura, Kou [1 ]
Tashiro, Naoki [1 ]
Shibuya, Hideki [1 ]
Nakahara, Kazuki [2 ]
Kishida, Yukiko [3 ]
Tamura, Kouichi [3 ]
Hisada, Tetsuya [1 ]
机构
[1] Tokyo Teishin Hosp, Dept Resp Med, Tokyo, Japan
[2] Tokyo Teishin Hosp, Dept Surg, Tokyo, Japan
[3] Tokyo Teishin Hosp, Dept Pathol, Tokyo, Japan
关键词
MALT lymphoma; thymus; trisomy; 18; Sjogren's syndrome; parotid gland; literature review; B-CELL LYMPHOMA; PRIMARY SJOGRENS-SYNDROME; LOW-GRADE; MALIGNANT-LYMPHOMA; CHROMOSOMAL TRANSLOCATION; CONCERTED ACTION; PATIENT; BCL10; CLASSIFICATION; IMMUNOGLOBULIN;
D O I
10.2169/internalmedicine.48.2424
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) of the thymus is rare and little is known about its karyotype abnormality. MALT lymphoma in general shows a good prognosis, but some reports suggest that the presence of trisomy 18 predicts recurrence. Here, we report a patient with MALT lymphoma of the thymus and the left parotid gland accompanied by Sjogren's syndrome. The karyotype analysis revealed that this is the first case of thymic MALT lymphoma with trisomy 18, which we believe is worth reporting. We also review cases with thymic MALT lymphoma previously reported in the literature.
引用
收藏
页码:2025 / 2032
页数:8
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