Molecularly imprinted curcumin nanoparticles decorated paper for electrochemical and fluorescence dual-mode sensing of bisphenol A

A molecularly imprinted paper-based analytical device (MIP-mu PAD) was developed for the sensing of bisphenol A (BPA). The platform was screen-printed onto a filter paper support, where the electrodes and the fluorescence mu PADs were designed. Owing to its dual electrochemical and fluorescence responses, molecularly imprinted curcumin nanoparticles were used to sense BPA. The mu PAD design was characterized by transmission electron microscopy, scanning electron microscopy, fluorescence spectroscopy, and electrochemical techniques. The sensor design comprised a wide linear range from 1 to 200 mu g L-1 with limits of detection of 0.47 +/- 0.2 and 0.62 +/- 0.3 mu g L-1 (LOD, S/N = 3) for electrochemical and fluorescence sensing, respectively. Furthermore, the system showed good analytical performance such as selectivity, stability, and reproducibility. The feasibility of the MIP-mu PAD was demonstrated for the sensing of BPA in seawater, foods, and polycarbonate plastic packaged water with recovery values of 97.2 and 101.8%.