L-proline catalyzed selective synthesis of 2-aryl-1-arylmethyl-1H-benzimidazoles

被引：145
|
作者：
Varala, Ravi [1 ]
Nasreen, Aayesha [1 ]
Enugala, Ramu [1 ]
Adapa, Srinivas R. [1 ]
机构：
[1] Indian Inst Chem Technol, Hyderabad 500007, Andhra Pradesh, India
来源：
TETRAHEDRON LETTERS | 2007年 / 48卷 / 01期
关键词：
D O I：
10.1016/j.tetlet.2006.11.010
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
L-Proline (10 mol %) was found to be a versatile organocatalyst for the selective synthesis of 2-aryl-1-arylmethyl-1-H-benzimidazoles from a wide range of substituted o-phenylenediamines and aldehydes in moderate to excellent isolated yields (32-95%) under mild conditions using chloroform as a solvent at ambient temperature. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码：69 / 72
页数：4
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