EVALUATION OF RIGHT VENTRICULAR DYSFUNCTION AND MORTALITY WITH CT ANGIOGRAPHY PARAMETERS OF ACUTE PULMONARY EMBOLISM

被引:1
作者
Melekoglu, Adem [1 ]
Ozkan, Seda [2 ]
Gunes, Serra Ozbal [3 ]
Cimen, Tolga [4 ]
机构
[1] Univ & Hlth Sci, Sisli Etfal Training & Res Hosp, Dept Emergency Med, Istanbul, Turkey
[2] Univ Hlth Sci, Diskapi Yildirim Beyazi Training & Res Hosp, Dept Emergency Med, TR-06145 Ankara, Turkey
[3] Univ Hlth Sci, Diskapi Yildirim Beyazit Training & Res Hosp, Dept Radiol, Ankara, Turkey
[4] Univ Hlth Sci, Diskapi Yildirim Beyazit Training & Res Hosp, Dept Cardiol, Ankara, Turkey
来源
ACTA MEDICA MEDITERRANEA | 2019年 / 35卷 / 05期
关键词
Pulmonary Embolism; Acute Disease; Computed Tomography Angiography; Right Ventricular Dysfunction; OBSTRUCTION SCORES; ECHOCARDIOGRAPHY; PREDICTOR; SEVERITY; INDEX;
D O I
10.19193/0393-6384_2019_5_407
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Introduction: Right ventricular dysfunction is an independent and significant predictor of a poor prognosis in patients with an acute pulmonary embolism. Right ventricular overload can be detected along with pulmonary embolism via computed tomography angiography. We aimed to evaluate the accuracy of CT angiography parameters in diagnosing right ventricular dysfunction and predicting mortality in acute pulmonary embolism. Materials and methods: One hundred and twenty-six patients were included in the study. Main pulmonary arterial diameters, right and left main pulmonary arterial diameters, and ventricular diameters and ratios were measured by obtaining a large sequence of thoracic CT angiography images. Qanadli scores and Qanadli obstruction indices were calculated. Echocardiography was performed in all patients to determine right ventricular dysfunction. Results: A significant difference in CT measurements was noted between patients who were diagnosed with right ventricular dilatation on echocardiography and those who were not (p<0.05). Regarding the diagnosis of right heart failure, CT angiography demonstrated a sensitivity of 89% in patients who were found to have a Right Ventricle/Left Ventricle diameter ratio >0.9. The AUCs for the diagnosis of right heart failure via CT angiography were 0.63 for the Qanadli score, 0.78 for the Right Ventricle/Left Ventricle diameter ratio, 0.71 for main pulmonary arterial diameter, and 0.79 for right ventricular diameter. The A UCs for the prediction of mortality based on CT angiography findings were 0.51 for the Qanadli score, 0.61 for the Right Ventricle/Left Ventricle diameter ratio, 0.53 for main pulmonary arterial diameter, and 0.55 for right ventricular diameter. Notably, increased main pulmonary arterial diameter, which was calculated via tomography, was related to a high systolic pulmonary artery pressure. Conclusion: CT angiography is an imaging technique that can be used to diagnose right ventricular dilatation in patients with acute pulmonary embolism and to determine disease prognosis and appropriate treatment strategies.
引用
收藏
页码:2593 / 2600
页数:8
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