The clinical significance and prognostic value of right ventricular wall tension in moderate or severe tricuspid regurgitation

被引：1

作者：

Saeed, Sahrai ^{[1
]}

Grigoryan, Karine ^{[2
]}

Smith, Jenna ^{[2
]}

Gill, Harminder ^{[3
]}

Freitas, Dario ^{[2
]}

Bleie, Oyvind ^{[1
]}

Chambers, John B. ^{[2
]}

Rajani, Ronak ^{[2
,3
]}

机构：

[1] Haukeland Hosp, Dept Heart Dis, Bergen, Norway

[2] Guys & St Thomas NHS Fdn Trust, Cardiothoracic Ctr, London, England

[3] Kings Coll London, Sch Biomed Engn & Imaging Sci, London, England

来源：

FUTURE CARDIOLOGY | 2021年 / 17卷 / 08期

关键词：

all-cause mortality; right ventricular systolic function; right ventricular wall tension; systolic pulmonary artery pressure; tricuspid annular plane systolic excursion; tricuspid regurgitation; EUROPEAN ASSOCIATION; AMERICAN SOCIETY; ECHOCARDIOGRAPHIC-ASSESSMENT; REGISTERED BRANCH; CANADIAN SOCIETY; TASK-FORCE; HEART; GUIDELINES; CARDIOLOGY; IMPACT;

D O I：

10.2217/fca-2020-0176

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: We aim to explore the determinants of right ventricular wall tension (RV WT [RV base-to-apex length multiplied by systolic pulmonary artery pressure] and association with all-cause mortality in patients with moderate-to-severe tricuspid regurgitation. Materials & methods: Of total, 180 patients (71 +/- 15years, 54% females) were included. An increased RV WT was defined as >3300 mmHgxmm. Results: Patients with increased RV WT (n = 85, 47%) were more likely to be male and taller than patients with normal RV WT. In a multivariable-adjusted model, increased RV WT was associated with a 2.6-fold higher risk of all-cause mortality (HR: 2.59, 95% CI: 1.65-4.06). Conclusion: In patients with significant tricuspid regurgitation, an increased RV WT was common, and associated with a 2.6-fold higher risk of all-cause mortality. Male sex was the only independent determinant.

引用

页码：1371 / 1379

页数：9