The Role of γδ T Cells in Systemic Lupus Erythematosus

被引：29

作者：

Wu, Meng ^{[1
]}

Yang, Jinhua ^{[1
]}

Li, Xiaofeng ^{[1
]}

Chen, Junwei ^{[1
]}

机构：

[1] Shanxi Med Univ, Hosp 2, Dept Rheumatol, Taiyuan 030001, Shanxi, Peoples R China

来源：

JOURNAL OF IMMUNOLOGY RESEARCH | 2016年 / 2016卷

关键词：

DENDRITIC CELLS; B-CELLS; PERIPHERAL-BLOOD; INTERFERON-GAMMA; RECEPTOR; ANTIGEN; SUBSET; DIFFERENTIATION; STIMULATION; EXPRESSION;

D O I：

10.1155/2016/2932531

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by the overproduction of autoantibodies against an array of nuclear and cytoplasmic antigens and affects multiple organs, such as the skin, joints, kidneys, and neuronal tissues. T cells have been recognized as important players in the development of SLE due to their functions in cytokine secretion, antigen presentation, and supporting B cells for antibody production gamma delta T cells are a minor population of T cells that play important roles in infection and tumor-associated disease. In recent years, the role of gamma delta T cells in autoimmune diseases has been investigated. In this review, we discussed the role of gamma delta T cells in the pathogenesis of SLE.

引用

页数：8

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