Cephalostatin support studies, part 23.: Chemospecific chromium[VI] catalyzed oxidation of C-H bonds at -40°C

被引：88

作者：

Lee, SM ^{[1
]}

Fuchs, PL ^{[1
]}

机构：

[1] Purdue Univ, Dept Chem, W Lafayette, IN 47907 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2002年 / 124卷 / 47期

关键词：

D O I：

10.1021/ja026734o

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

H5IO6 in the presence of catalytic chromoyl diacetate is a powerful method for oxidation of C-H bonds. Tertiary and oxygen activated C-H bonds are oxidized to tertiary alcohols or ketones at temperatures as low as -40 °C. The putative reagent is neutral dioxoperoxy chromium[VI] which undergoes C-H oxidation with retention of stereochemistry. This reagent appears to be the first reagent capable of oxidation of a C-H bond in the presence of an olefin without concomitant epoxidation. Copyright © 2002 American Chemical Society.

引用

页码：13978 / 13979

页数：2

共 30 条

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