Are Midsagittal Tissue Bridges Predictive of Outcome After Cervical Spinal Cord Injury?

被引：53
|
作者：
Huber, Eveline [1 ]
Lachappelle, Patrice [1 ]
Sutter, Reto [2 ]
Curt, Armin [1 ]
Freund, Patrick [1 ,3 ,4 ,5 ]
机构：
[1] Balgrist Univ Hosp, Spinal Cord Injury Ctr, Forchstr 340, CH-8008 Zurich, Switzerland
[2] Balgrist Univ Hosp, Radiol, Zurich, Switzerland
[3] UCL, Inst Neurol, Wellcome Trust Ctr Neuroimaging, London, England
[4] UCL, UCL Inst Neurol, Dept Brain Repair & Rehabil, London, England
[5] Max Planck Inst Human Cognit & Brain Sci, Dept Neurophys, Leipzig, Germany
来源：
ANNALS OF NEUROLOGY | 2017年 / 81卷 / 05期
关键词：
CONTUSION; RECOVERY; MR; REGENERATION; SYSTEM; LESION; RAT;
D O I：
10.1002/ana.24932
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
T-2-weighted scans provided data on the extent and dynamics of neuronal tissue damage and midsagittal tissue bridges at the epicenter of traumatic cervical spinal cord lesions in 24 subacute tetraplegic patients. At 1 month postinjury, smaller lesion area and midsagittal tissue bridges identified those patients with lower extremity evoked potentials and better clinical recovery. Wider midsagittal tissue bridges and smaller lesions at 1 month post-injury were associated with neurological and functional recovery at 1-year follow-up. Neuroimaging biomarkers of lesion size and midsagittal tissue bridges are potential outcome predictors and patient stratifiers in both subacute and chronic clinical trials.
引用
收藏
页码：740 / 748
页数：9
相关论文
共 50 条
  • [41] CHANGES IN CHOLINE ACETYLTRANFERASE DISTRIBUTION IN THE CERVICAL SPINAL-CORD AFTER REVERSIBLE CERVICAL SPINAL-CORD INJURY
    NAKAMURA, M
    FUJIMURA, Y
    YATO, Y
    WATANABE, M
    IWAMOTO, Y
    PARAPLEGIA, 1994, 32 (11): : 752 - 758
  • [42] Spinal Cord Injury Induced by a Cervical Spinal Cord Stimulator
    Falowski, Steven
    Ooi, Yinn Cher
    Sabesan, Arvind
    Sharan, Ashwini
    NEUROMODULATION, 2011, 14 (01): : 34 - 36
  • [43] Clinical Predictors of Neurological Outcome within 72 h after Traumatic Cervical Spinal Cord Injury
    Qiu, Zhi
    Wang, Fangyong
    Hong, Yi
    Zhang, Junwei
    Tang, Hehu
    Li, Xiang
    Jiang, Shudong
    Lv, Zhen
    Liu, Shujia
    Chen, Shizheng
    Liu, Jiesheng
    SCIENTIFIC REPORTS, 2016, 6
  • [44] Functional outcome after traumatic cervical spinal cord injury: Can adolescents be truly compared to adults?
    Wirtz, Mirja M.
    Griessenauer, Christoph J.
    EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY, 2019, 23 (02) : 229 - 230
  • [45] Clinical Predictors of Neurological Outcome within 72 h after Traumatic Cervical Spinal Cord Injury
    Zhi Qiu
    Fangyong Wang
    Yi Hong
    Junwei Zhang
    Hehu Tang
    Xiang Li
    Shudong Jiang
    Zhen Lv
    Shujia Liu
    Shizheng Chen
    Jiesheng Liu
    Scientific Reports, 6
  • [46] Clinical Influence of Cervical Spinal Canal Stenosis on Neurological Outcome after Traumatic Cervical Spinal Cord Injury without Major Fracture or Dislocation
    Takao, Tsuneaki
    Okada, Seiji
    Morishita, Yuichiro
    Maeda, Takeshi
    Kubota, Kensuke
    Ideta, Ryosuke
    Mori, Eiji
    Yugue, Itaru
    Kawano, Osamu
    Sakai, Hiroaki
    Ueta, Takayoshi
    Shiba, Keiichiro
    ASIAN SPINE JOURNAL, 2016, 10 (03) : 536 - 542
  • [47] Electrical epidural stimulation of the cervical spinal cord: implications for spinal respiratory neuroplasticity after spinal cord injury
    Malone, Ian G.
    Nosacka, Rachel L.
    Nash, Marissa A.
    Otto, Kevin J.
    Dale, Erica A.
    JOURNAL OF NEUROPHYSIOLOGY, 2021, 126 (02) : 607 - 626
  • [48] Predictive factors for irreversible motor paralysis following cervical spinal cord injury
    Konomi, Tsunehiko
    Suda, Kota
    Ozaki, Masahiro
    Harmon, Satoko Matsumoto
    Komatsu, Miki
    Iimoto, Seiji
    Tsuji, Osahiko
    Minami, Akio
    Takahata, Masahiko
    Iwasaki, Norimasa
    Matsumoto, Morio
    Nakamura, Masaya
    SPINAL CORD, 2021, 59 (05) : 554 - 562
  • [49] Predictive factors for irreversible motor paralysis following cervical spinal cord injury
    Tsunehiko Konomi
    Kota Suda
    Masahiro Ozaki
    Satoko Matsumoto Harmon
    Miki Komatsu
    Seiji Iimoto
    Osahiko Tsuji
    Akio Minami
    Masahiko Takahata
    Norimasa Iwasaki
    Morio Matsumoto
    Masaya Nakamura
    Spinal Cord, 2021, 59 : 554 - 562
  • [50] Injury and demographic factors predictive of disparities in earnings after spinal cord injury
    Krause, James S.
    Terza, Joseph V.
    ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, 2006, 87 (10): : 1318 - 1326
12345