Are Midsagittal Tissue Bridges Predictive of Outcome After Cervical Spinal Cord Injury?

被引：53
|
作者：
Huber, Eveline [1 ]
Lachappelle, Patrice [1 ]
Sutter, Reto [2 ]
Curt, Armin [1 ]
Freund, Patrick [1 ,3 ,4 ,5 ]
机构：
[1] Balgrist Univ Hosp, Spinal Cord Injury Ctr, Forchstr 340, CH-8008 Zurich, Switzerland
[2] Balgrist Univ Hosp, Radiol, Zurich, Switzerland
[3] UCL, Inst Neurol, Wellcome Trust Ctr Neuroimaging, London, England
[4] UCL, UCL Inst Neurol, Dept Brain Repair & Rehabil, London, England
[5] Max Planck Inst Human Cognit & Brain Sci, Dept Neurophys, Leipzig, Germany
来源：
ANNALS OF NEUROLOGY | 2017年 / 81卷 / 05期
关键词：
CONTUSION; RECOVERY; MR; REGENERATION; SYSTEM; LESION; RAT;
D O I：
10.1002/ana.24932
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
T-2-weighted scans provided data on the extent and dynamics of neuronal tissue damage and midsagittal tissue bridges at the epicenter of traumatic cervical spinal cord lesions in 24 subacute tetraplegic patients. At 1 month postinjury, smaller lesion area and midsagittal tissue bridges identified those patients with lower extremity evoked potentials and better clinical recovery. Wider midsagittal tissue bridges and smaller lesions at 1 month post-injury were associated with neurological and functional recovery at 1-year follow-up. Neuroimaging biomarkers of lesion size and midsagittal tissue bridges are potential outcome predictors and patient stratifiers in both subacute and chronic clinical trials.
引用
收藏
页码：740 / 748
页数：9
相关论文
共 50 条
  • [31] BRONCHIAL HYPERRESPONSIVENESS AFTER CERVICAL SPINAL-CORD INJURY
    DICPINIGAITIS, PV
    SPUNGEN, AM
    BAUMAN, WA
    ABSGARTEN, A
    ALMENOFF, PL
    CHEST, 1994, 105 (04) : 1073 - 1076
  • [32] A Case of Dizziness After Traumatic Cervical Spinal Cord Injury
    Sawicki, Carolyn P.
    Zimcik, Heather
    McGillivray, Colleen
    AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION, 2020, 99 (12) : 1191 - 1194
  • [33] Neural Cardiovascular Function After Cervical Spinal Cord Injury
    Aslan, Sevda C.
    Krassioukov, Andrei
    Harkema, Susan J.
    2009 4TH INTERNATIONAL IEEE/EMBS CONFERENCE ON NEURAL ENGINEERING, 2009, : 547 - +
  • [34] Predictive factors of destination at discharge after spinal cord injury
    Barbara-Bataller, E.
    Mendez-Suarez, J. L.
    Aleman-Sanchez, C.
    Penaloza-Polo, P.
    Sanchez-Enriquez, J.
    Saavedra-Santana, P.
    NEUROLOGIA, 2024, 39 (05): : 432 - 441
  • [35] Effect of Durotomy versus Myelotomy on Tissue Sparing and Functional Outcome after Spinal Cord Injury
    Khaing, Zin Z.
    Cates, Lindsay N.
    Dewees, Dane M.
    Hyde, Jeffrey E.
    Gaing, Ashley
    Birjandian, Zeinab
    Hofstetter, Christoph P.
    JOURNAL OF NEUROTRAUMA, 2021, 38 (06) : 746 - 755
  • [36] ELECTROPHYSIOLOGIC CHANGES IN LUMBAR SPINAL-CORD AFTER CERVICAL CORD INJURY
    AISEN, ML
    BROWN, W
    RUBIN, M
    NEUROLOGY, 1992, 42 (03) : 623 - 626
  • [37] Cervical Flexion Myelopathy Eleven Years after a Cervical Spinal Cord Injury
    Nakano, Hiroto
    Sakai, Kenji
    Iwasa, Kazuo
    Yamada, Masahito
    INTERNAL MEDICINE, 2017, 56 (16) : 2213 - 2215
  • [38] Trigemino-cervical-spinal reflexes after traumatic spinal cord injury
    Nardone, Raffaele
    Hoeller, Yvonne
    Orioli, Andrea
    Brigo, Francesco
    Christova, Monica
    Tezzon, Frediano
    Golaszewski, Stefan
    Trinka, Eugen
    CLINICAL NEUROPHYSIOLOGY, 2015, 126 (05) : 983 - 986
  • [39] Role of durotomy on function outcome, tissue sparing, inflammation, and tissue stiffness after spinal cord injury in rats
    Jin, Chen
    Wang, Kaiwei
    Ren, Yilong
    Li, Yi
    Wang, Zhanwei
    Cheng, Liming
    Xie, Ning
    MEDCOMM, 2024, 5 (04):
  • [40] Cervical Spinal Cord Injury After Thoracic Spinal Instrumentation A Case Series
    Youlo, Sylvester T.
    Merrick, Michael T.
    Cassidy, Jeffrey A.
    Halanski, Matthew A.
    SPINE, 2013, 38 (26) : E1704 - E1708
12345