Oxidation behaviour in prosthetic UHMWPE components sterilised with high-energy radiation in the presence of oxygen

被引：48

作者：

Bracco, P.

Brunella, V.

Luda, M. P.

del Prever, E. M. Brach

Zanetti, M.

Costa, L.

机构：

[1] Univ Turin, Dipartimento Chim Inorgan & Chim Fis, I-10125 Turin, Italy

[2] NIS, Ctr Excellence, I-10125 Turin, Italy

[3] Univ Turin, Ctr Traumatol Ortoped, Clin Ortoped 1, I-10126 Turin, Italy

来源：

POLYMER DEGRADATION AND STABILITY | 2006年 / 91卷 / 12期

关键词：

UHMWPE; gamma radiation; oxidation; hydroperoxides; FTIR;

D O I：

10.1016/j.polymdegradstab.2006.08.002

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

UHMWPE orthopaedic components are commonly sterilised by high-energy radiation. In the last 10 years, many studies pointed out that irradiation in air can lead to an oxidative degradation of the polymer, but the correlation between the sterilisation conditions and the amount and distribution of the oxidation products in the prosthetic components is still unclear. In the present study, a large number of never implanted, gamma sterilised prosthetic components have been analysed by using FTIR microspectroscopy and derivatisation techniques. Based on the obtained oxidation profiles, the samples were divided into three groups and a correlation between the oxidation products and their distribution and some sterilisation parameters have been proposed. Presence of oxygen, dose rate and temperature were found to play a highly relevant role in determining the whole oxidation degree and its distribution in the UHMWPE components. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：3057 / 3064

页数：8

共 24 条

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