Electronics method to advance the coincidence time resolution with bismuth germanate

被引:48
作者
Cates, Joshua W. [1 ]
Levin, Craig S. [2 ]
机构
[1] Lawrence Berkeley Natl Lab, Appl Nucl Phys, Berkeley, CA 94720 USA
[2] Stanford Univ, Sch Med, Stanford, CA 94305 USA
关键词
time-of-flight PET; positron emission tomography; bismuth germanate; PET DETECTORS; ANALOG;
D O I
10.1088/1361-6560/ab31e3
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Exploiting the moderate Cherenkov yield from 511 keV photoelectric interactions in bismuth germanate (BGO) scintillators enables one to achieve a level of coincidence time resolution (CTR) appropriate for time-of-flight positron emission tomography (TOF-PET). For this approach, owing to the low number of promptly emitted light photons, single photon time resolution (SPTR) can have a stronger influence on achievable CTR. We have previously shown readout techniques that reduce effective device capacitance of large area silicon photomultipliers (SiPMs) can yield improvements in single photon response shape that minimize the influence of electronic noise on SPTR. With these techniques, sub-100 ps FWHM SPTR can be achieved with 4 x 4 mm(2) FBK near-ultra-violet high density (NW-HD) SiPMs. These sensors are also useful for detecting Cherenkov light due to relatively high photon detection efficiency for UV light. In this work, we measured CTR for BGO crystals coupled to FBK NUV-HD SiPMs with a passive bootstrapping readout circuit that effectively reduces the SiPM device capacitance. A range of CTR values between 200 +/- 3 and 277 +/- 7 ps FWHM were measured for 3 x 3 x 3 and 3 x 3 x 15 mm(3) crystals, respectively. This readout technique provides a relatively simple approach to achieve state-of-the-art CTR performance using BGO crystals for TOF-PET.
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页数:8
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共 25 条
  • [1] BGO as a hybrid scintillator / Cherenkov radiator for cost-effective time-of-flight PET
    Brunner, S. E.
    Schaart, D. R.
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2017, 62 (11) : 4421 - 4439
  • [2] Improved single photon time resolution for analog SiPMs with front end readout that reduces influence of electronic noise
    Cates, Joshua W.
    Gundacker, Stefan
    Auffray, Etiennette
    Lecoq, Paul
    Levin, Craig S.
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2018, 63 (18)
  • [3] Evaluation of a clinical TOF-PET detector design that achieves ≤100 ps coincidence time resolution
    Cates, Joshua W.
    Levin, Craig S.
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2018, 63 (11)
  • [4] Advances in coincidence time resolution for PET
    Cates, Joshua W.
    Levin, Craig S.
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2016, 61 (06) : 2255 - 2264
  • [5] Analytical calculation of the lower bound on timing resolution for PET scintillation detectors comprising high-aspect-ratio crystal elements
    Cates, Joshua W.
    Vinke, Ruud
    Levin, Craig S.
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2015, 60 (13) : 5141 - 5161
  • [6] Total-Body PET: Maximizing Sensitivity to Create New Opportunities for Clinical Research and Patient Care
    Cherry, Simon R.
    Jones, Terry
    Karp, Joel S.
    Qi, Jinyi
    Moses, William W.
    Badawi, Ramsey D.
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2018, 59 (01) : 3 - 12
  • [7] Analog Circuit for Timing Measurements With Large Area SiPMs Coupled to LYSO Crystals
    Gola, Alberto
    Piemonte, Claudio
    Tarolli, Alessandro
    [J]. IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2013, 60 (02) : 1296 - 1302
  • [8] State of the art timing in TOF-PET detectors with LuAG, GAGG and L(Y)SO scintillators of various sizes coupled to FBK-SiPMs
    Gundacker, S.
    Acerbi, F.
    Auffray, E.
    Ferri, A.
    Gola, A.
    Nemallapudi, M. V.
    Paternoster, G.
    Piemonte, C.
    Lecoq, P.
    [J]. JOURNAL OF INSTRUMENTATION, 2016, 11
  • [9] On the comparison of analog and digital SiPM readout in terms of expected timing performance
    Gundacker, S.
    Auffray, E.
    Jarron, P.
    Meyer, T.
    Lecoq, P.
    [J]. NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2015, 787 : 6 - 11
  • [10] Time of flight positron emission tomography towards 100ps resolution with L(Y)SO: an experimental and theoretical analysis
    Gundacker, S.
    Auffray, E.
    Frisch, B.
    Jarron, P.
    Knapitsch, A.
    Meyer, T.
    Pizzichemi, M.
    Lecoq, P.
    [J]. JOURNAL OF INSTRUMENTATION, 2013, 8