The evolving potential for pediatric ex vivo lung perfusion

被引:9
作者
Luc, Jessica G. Y. [1 ,2 ]
Nagendran, Jayan [1 ,2 ,3 ,4 ]
机构
[1] Univ Alberta, Fac Med & Dent, Dept Surg, Div Cardiac Surg, Edmonton, AB T6G 2B7, Canada
[2] Mazankowski Alberta Heart Inst, 2D2-18 WMC,8440-112 St, Edmonton, AB T6G 2B7, Canada
[3] Alberta Transplant Inst, Edmonton, AB, Canada
[4] Canadian Natl Transplant Res Program, Edmonton, AB, Canada
关键词
allograft function; pediatric lung transplantation; outcome; EXTRACORPOREAL MEMBRANE-OXYGENATION; OVERCOME SIZE DISPARITIES; ORGAN CARE SYSTEM; CARDIAC DEATH; LOBAR TRANSPLANTATION; ISCHEMIC TIME; DONOR ORGANS; DONATION; HEART; CHILDREN;
D O I
10.1111/petr.12653
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Despite the rise in the number of adult lung transplantations performed, rates of pediatric lung transplantation remain low. Lung transplantation is an accepted therapy for pediatric end-stage lung disease; however, it is limited by a shortage of donor organs. EVLP has emerged as a platform for assessment and preservation of donor lung function. EVLP has been adopted in adult lung transplantation and has successfully led to increased adult lung transplantations and donor lung utilization. We discuss the future implications of EVLP utilization, specifically, its potential evolving role in overcoming donor shortages in smaller children and adolescents to improve the quality and outcomes of lung transplantation in pediatric patients.
引用
收藏
页码:13 / 22
页数:10
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