Development of the immune system and immunological protection in marsupial pouch young

被引:88
作者
Old, JM [1 ]
Deane, EM [1 ]
机构
[1] Univ Western Sydney Nepean, Sch Sci, Kingswood, NSW 2747, Australia
基金
澳大利亚研究理事会;
关键词
ontogeny; marsupials; immunocompetence;
D O I
10.1016/S0145-305X(00)00008-2
中图分类号
S9 [水产、渔业];
学科分类号
0908 ;
摘要
At birth the tissues of marsupial immune system are underdeveloped. The young animal is not immunocompetent. Histological and immunohistochemical studies of pouch young epithelial tissues provide a clear picture of tissue development but the timing of onset of immunocompetence awaits definition. The survival of the neonatal marsupial in a microbially rich environment is dependent on maternal strategies, including immunoglobulin transfer via milk and, in some species, prenatally via the yolk sac placenta. It is also likely that pouch secretions play a role. This review summarizes our current knowledge of the pathway of immunological development in marsupials and the protection and threats afforded by the pouch environment. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:445 / 454
页数:10
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