Integration of multiple active sites on large-pore mesoporous silica for enantioselective tandem reactions

被引：29

作者：

Xia, Xuelin ^{[1
]}

Meng, Jingjing ^{[1
]}

Wu, Hanxin ^{[1
]}

Cheng, Tanyu ^{[1
]}

Liu, Guohua ^{[1
]}

机构：

[1] Shanghai Normal Univ, Key Lab Rare Earth Funct Mat, Key Lab Resource Chem, Minist Educ, Shanghai 200234, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 10期

关键词：

ASYMMETRIC TRANSFER HYDROGENATION; BETA-ADRENERGIC BLOCKERS; AROMATIC KETONES; HETEROGENEOUS CATALYSIS; BIFUNCTIONAL CATALYST; COMPLEXES; ACID; HYDRATION; STRATEGY; WATER;

D O I：

10.1039/c6cc09008g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Facile construction of a multifunctional heterogeneous catalyst through the assembly of Au/carbene and chiral ruthenium/diamine dual complexes in large-pore mesoporous silica was developed. This enables an efficient one-pot hydration-asymmetric transfer hydrogenation enantio-selective tandem reaction of haloalkynes, affording chiral halohydrins with up to 99% enantioselectivity. Combined multifunctionalities, such as substrate-promoted silanol-functionality, BF4- anion-bonding gold/carbene and covalent-bonding chiral ruthenium/diamine active centers, contributed cooperatively to the catalytic performance.

引用

页码：1638 / 1641

页数：4

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