Electrochemical Detection of Serotonin Using Polyethylenedioxythiophene and Core-Shell Molecularly Imprinted Polymer Nanoparticles

被引:0
|
作者
Introna, Barbara [1 ]
Mazzotta, Elisabetta [1 ]
Turco, Antonio [1 ]
Malitesta, Cosimino [1 ]
Mohammadi, Reza [2 ,4 ]
Ramezany, Farid [2 ,5 ]
Sellergren, Boerje [2 ,3 ]
机构
[1] Univ Salento, Dipartimento Sci & Tecnol Biol Ambientali, Lab Chim Analit, I-73100 Lecce, Italy
[2] Tech Univ Dortmund, Fac Chem & Chem Biol, D-44221 Dortmund, Germany
[3] Malmo Univ, Fac Hlth & Soc, Dept Biomed Sci, SE-20506 Malmo, Sweden
[4] Univ Tabriz, Fac Chem, Tabriz, Iran
[5] Univ Tehran Med Sci, Fac Tradit Med, Dept Tradit Pharmaceut, Tehran, Iran
来源
关键词
molecularly imprinted polymers; core shell nanoparticles; electrochemical sensors; polyethylenedioxythiophene (PEDOT); serotonin; FILMS;
D O I
暂无
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Preliminary results on detection of neurotransmitter serotonin using an electrochemical sensor, based on a composite made of core-shell molecularly imprinted polymer (MIP) nanoparticles and polyethylenedioxythiophene (PEDOT) film are described. MIP is grown on pre-formed SiO2 nanobeads by surface imprinting via reversible addition-fragmentation chain-transfer (RAFT) polymerization. The core-shell Ser-MIP@SiO2 nanobeads are integrated onto electrode surfaces to develop an electrochemical sensors for analyte serotonin. The entrapment of core-shell Ser-MIP@SiO2 nanobeads by the electropolymerization of PEDOT in an upside-down electrochemical cell is performed and preliminary results in sensing application are presented.
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页数:4
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