BRAF Inhibitor-Driven Tumor Proliferation in a KRAS-Mutated Colon Carcinoma Is Not Overcome by MEK1/2 Inhibition

被引：43

作者：

Andrews, Miles C. ^{[1
]}

Behren, Andreas ^{[2
]}

Chionh, Fiona ^{[2
]}

Mariadason, John ^{[2
]}

Vella, Laura J. ^{[2
]}

Do, Hongdo ^{[3
]}

Dobrovic, Alexander ^{[3
]}

Tebbutt, Niall ^{[1
]}

Cebon, Jonathan ^{[1
]}

机构：

[1] Austin Hlth, Joint Ludwig Austin Oncol Unit, Melbourne, Vic, Australia

[2] Ludwig Inst Canc Res, Austin Branch, Melbourne, Vic, Australia

[3] Peter MacCallum Canc Ctr, Melbourne, Vic, Australia

来源：

JOURNAL OF CLINICAL ONCOLOGY | 2013年 / 31卷 / 35期

基金：

英国医学研究理事会;

关键词：

SQUAMOUS-CELL CARCINOMAS; ADVANCED MELANOMA; RAF INHIBITORS; MUTATIONS; SURVIVAL; V600E;

D O I：

10.1200/JCO.2013.50.4118

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：E448 / E451

页数：4

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