THE EFFECT OF FLUORINE ON THE DEVELOPING HUMAN BRAIN

被引：0

作者：

Du, Li ^{[1
]}

Wan, Changwu ^{[1
]}

Cao, Xumao ^{[1
]}

Liu, Jialiu ^{[1
]}

机构：

[1] Guiyang Med Coll, Dept Pathol, Guiyang 550001, Peoples R China

来源：

FLUORIDE | 2008年 / 41卷 / 04期

关键词：

Brain damage; Computer data treatment; Electron microscopy; Fetal fluoride; Fluoride poisoning; Human fetuses; Image processing; Neuron development;

D O I：

暂无

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Fifteen fetuses from an endemic fluorosis area that were aborted therapeutically at the 5th-8th month of gestation were compared with 16 aborted fetuses from a non-endemic area. Stereological study of the brains showed that the numerical density of the neuron volume and the undifferentiated neuroblasts as well as the nucleus-cytoplasm ratio of the neurons were increased. The mean volume of the neurons, however, was reduced. The numerical density of volume, the volume density, and the surface density of the mitochondria were significantly reduced. The results showed that chronic fluorosis in the course of intrauterine fetal life may produce certain harmful effects on the developing brain of the fetus.

引用

页码：327 / 330

页数：4

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