High-throughput multiclass method for antibiotic residue analysis by liquid chromatography-tandem mass spectrometry

被引：89

作者：

Chico, J. ^{[1
]}

Rubies, A. ^{[2
]}

Centrich, F. ^{[2
]}

Companyo, R. ^{[1
]}

Prat, M. D. ^{[1
]}

Granados, M. ^{[1
]}

机构：

[1] Univ Barcelona, Fac Quim, Dept Quim Analit, E-08028 Barcelona, Spain

[2] Lab Agencia Salut Publ Barcelona, Area Analisi Organ, Serv Quim, Barcelona 08001, Spain

来源：

JOURNAL OF CHROMATOGRAPHY A | 2008年 / 1213卷 / 02期

关键词：

Food analysis; Sulfonamides; Quinolones; Penicillins; Tetracyclines; Macrolides; LC-MS/MS;

D O I：

10.1016/j.chroma.2008.10.023

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A simple and rapid method has been developed for the residue analysis of 39 antibiotics (tetracyclines, quinolones, penicillins, sulfonamides and macrolides) in foodstuffs of animal origin. The method combines an effective extraction technique, which uses water-methanol as extracting solvent, with ultra-high-pressure liquid chromatography-tandem mass spectrometry, allowing both confirmation and quantification in a single chromatographic run. The multiresidue method has been validated in chicken muscle matrix according to European Union Decision 2002/657/EC. It has been implemented as a routine method in a Public Health Laboratory, instead of the five plates test and LC methods previously used. (c) 2008 Elsevier B.V. All rights reserved.

引用

页码：189 / 199

页数：11

共 50 条

[1] High-throughput multiclass screening method for antibiotic residue analysis in meat using liquid chromatography-tandem mass spectrometry: a novel minimum sample preparation procedure
Bittencourt, M. S.
Martins, M. T.
de Albuquerque, F. G. S.
Barreto, F.
Hoff, R.
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, 2012, 29 (04): : 508 - 516
[2] Development and validation of a multiclass method for the analysis of antibiotic residues in eggs by liquid chromatography-tandem mass spectrometry
Jimenez, V.
Rubies, A.
Centrich, F.
Companyo, R.
Guiteras, J.
JOURNAL OF CHROMATOGRAPHY A, 2011, 1218 (11) : 1443 - 1451
[3] Multiclass Analysis of Antibiotic Residues in Honey by Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry
Martinez Vidal, Jose Luis
del Mar Aguilera-Luiz, Maria
Romero-Gonzalez, Roberto
Garrido Frenich, Antonia
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2009, 57 (05) : 1760 - 1767
[4] Validation of a high-throughput liquid chromatography-tandem mass spectrometry method for urinary cortisol and cortisone
Taylor, RL
Machacek, D
Singh, RJ
CLINICAL CHEMISTRY, 2002, 48 (09) : 1511 - 1519
[5] High-throughput plasma docetaxel quantification by liquid chromatography-tandem mass spectrometry
Corona, Giuseppe
Elia, Caterina
Casetta, Bruno
Frustaci, Sergio
Toffoli, Giuseppe
CLINICA CHIMICA ACTA, 2011, 412 (3-4) : 358 - 364
[6] Development of a Method for the Analysis of Multiclass Antibiotic Residues in Milk Using QuEChERS and Liquid Chromatography-Tandem Mass Spectrometry
Wang, Yuan-long
Liu, Zhen-min
Ren, Jing
Guo, Ben-heng
FOODBORNE PATHOGENS AND DISEASE, 2015, 12 (08) : 693 - 703
[7] Multiclass method for antimicrobial analysis in animal feeds by liquid chromatography-tandem mass spectrometry
Borras, S.
Companyo, R.
Guiteras, J.
Bosch, J.
Medina, M.
Termes, S.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2013, 405 (26) : 8475 - 8486
[8] A liquid chromatography-tandem mass spectrometry method for fluazifop residue analysis in crops
Bolygo, E
Boseley, A
FRESENIUS JOURNAL OF ANALYTICAL CHEMISTRY, 2000, 368 (08): : 816 - 819
[9] A liquid chromatography-tandem mass spectrometry method for fluazifop residue analysis in crops
E. Bolygo
A. Boseley
Fresenius' Journal of Analytical Chemistry, 2000, 368 : 816 - 819
[10] A simple high-throughput method for the determination of plasma methylmalonic acid by liquid chromatography-tandem mass spectrometry
Blom, Henk J.
van Rooij, Arno
Hogeveen, Marije
CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2007, 45 (05) : 645 - 650

← 1 2 3 4 5 →