Doppler photoacoustic and Doppler ultrasound in blood with optical contrast agent

被引:2
作者
Sheinfeld, Adi [1 ]
Eyal, Avishay [1 ]
机构
[1] Tel Aviv Univ, Sch Elect Engn, IL-69978 Tel Aviv, Israel
来源
PHOTONS PLUS ULTRASOUND: IMAGING AND SENSING 2013 | 2013年 / 8581卷
关键词
Photoacoustic imaging; Flow measurement; Doppler; FLOW;
D O I
10.1117/12.2000906
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Photoacoustic Doppler flowmetry as well as Doppler ultrasound were performed in acoustic resolution regime on tubes filled with flowing blood with indocyanine green (ICG) at different concentrations. The photoacoustic excitation utilized a pair of directly-modulated fiber-coupled 830nm laser-diodes, modulated with either CW or tone-bursts for depthresolved measurements. The amplitude of the Doppler peak in photoacoustic Doppler measurements was found to be proportional to the ICG concentration. Photoacoustic Doppler was measured in ICG at human safe concentrations, but not in whole blood. Comparing the results between the two modalities implied that using a wavelength with higher optical absorption may improve the photoacoustic signal in blood.
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页数:7
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