Metastasis of Uveal Melanoma in Bladder: Presentation of Two Cases and Review of the Literature

Objective: Secondary urinary bladder tumors account for 2% of neoplasms in this location. Melanoma is the neoplasm that most frequently produces distant metastases in the bladder. Despite its low prevalence, it should be a possible diagnosis to consider facing urological symptoms, due to the existence of targeted therapies. Method: We present two cases of uveal melanoma metastasis in the bladder, their characteristics, and a review of the literature.Result: In this paper we present the histological characteristics and complementary techniques for the diagnosis of bladder metastases of melanoma and propose their inclusion among the possible differential diagnoses for bladder neoplasms.Conclusions: Given that there are currently targeted therapies against melanoma, the relevance of their inclusion in the differ-ential diagnosis of bladder tumors stands out.