Have guidelines addressing physical activity been established in nonalcoholic fatty liver disease?

被引：52

作者：

Finelli, Carmine ^{[2
]}

Tarantino, Giovanni ^{[1
]}

机构：

[1] Univ Naples Federico II, Med Sch Naples, Dept Clin & Expt Med, I-80131 Naples, Italy

[2] Stella Maris Mediterraneum Fdn, Ctr Obes & Eating Disorder, I-80035 Potenza, Italy

来源：

WORLD JOURNAL OF GASTROENTEROLOGY | 2012年 / 18卷 / 46期

关键词：

Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Physical activity; Diet; ACTIVATED PROTEIN-KINASE; COMBINED ELECTRICAL-STIMULATION; HEPATIC INSULIN-RESISTANCE; ELEMENT-BINDING PROTEIN; METABOLIC SYNDROME; SKELETAL-MUSCLE; LIFE-STYLE; ELDERLY-PEOPLE; GROWTH-HORMONE; RISK-FACTORS;

D O I：

10.3748/wjg.v18.i46.6790

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The purpose of this review was to highlight, in relation to the currently accepted pathophysiology of non-alcoholic fatty liver disease (NAFLD), the known exercise habits of patients with NAFLD and to detail the benefits of lifestyle modification with exercise (and/or physical activity) on parameters of metabolic syndrome. More rigorous, controlled studies of longer duration and defined histopathological end-points comparing exercise alone and other treatment are needed before better, evidence-based physical activity modification guidelines can be established, since several questions remain unanswered. (C) 2012 Baishideng. All rights reserved.

引用

页码：6790 / 6800

页数：11

共 103 条

[1]

Al-Mamari Ali, 2009, Oman Med J, V24, P173, DOI 10.5001/omj.2009.34

[2] Cytoplasmic Polyadenylation Element Binding Protein Deficiency Stimulates PTEN and Stat3 mRNA Translation and Induces Hepatic Insulin Resistance [J].

Alexandrov, Ilya M. ;

Ivshina, Maria ;

Jung, Dae Young ;

Friedline, Randall ;

Ko, Hwi Jin ;

Xu, Mei ;

O'Sullivan-Murphy, Bryan ;

Bortell, Rita ;

Huang, Yen-Tsung ;

Urano, Fumihiko ;

Kim, Jason K. ;

Richter, Joel D. .

PLOS GENETICS, 2012, 8 (01)

[3]

Allen TL, 2011, HANDB EXP PHARMACOL, V203, P179, DOI 10.1007/978-3-642-17214-4_9

[4] Type 2 Diabetes Is Associated with Altered NF-κB DNA Binding Activity, JNK Phosphorylation, and AMPK Phosphorylation in Skeletal Muscle after LPS [J].

Andreasen, Anne Sofie ;

Kelly, Meghan ;

Berg, Ronan Martin Griffin ;

Moller, Kirsten ;

Pedersen, Bente Klarlund .

PLOS ONE, 2011, 6 (09)

[5] Dietary Exercise as a Novel Strategy for the Prevention and Treatment of Metabolic Syndrome: Effects on Skeletal Muscle Function [J].

Aoi, Wataru ;

Naito, Yuji ;

Yoshikawa, Toshikazu .

JOURNAL OF NUTRITION AND METABOLISM, 2011, 2011

[6] Should Adipokines be Considered in the Choice of the Treatment of Obesity-Related Health Problems? [J].

Athyros, Vasilios G. ;

Tziomalos, Konstantinos ;

Karagiannis, Asterios ;

Anagnostis, Panagiotis ;

Mikhailidis, Dimitri P. .

CURRENT DRUG TARGETS, 2010, 11 (01) :122-135

[7] Strategies for reducing body fat mass: effects of liposuction and exercise on cardiovascular risk factors and adiposity [J].

Benatti, Fabiana Braga ;

Lira, Fabio Santos ;

Oyama, Lila Missae ;

da Penha Oller do Nascimento, Cludia Maria ;

Lancha Junior, Antonio Herbert .

DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY, 2011, 4 :141-154

[8] The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans [J].

Benhamed, Fadila ;

Denechaud, Pierre-Damien ;

Lemoine, Maud ;

Robichon, Celine ;

Moldes, Marthe ;

Bertrand-Michel, Justine ;

Ratziu, Vlad ;

Serfaty, Lawrence ;

Housset, Chantal ;

Capeau, Jacqueline ;

Girard, Jean ;

Guillou, Herve ;

Postic, Catherine .

JOURNAL OF CLINICAL INVESTIGATION, 2012, 122 (06) :2176-2194

[9] Leptin suppresses stearoyl-CoA desaturase 1 by mechanisms independent of insulin and sterol regulatory element-binding protein-1c [J].

Biddinger, Sudha B. ;

Miyazaki, Makoto ;

Boucher, Jeremie ;

Ntambi, James M. ;

Kahn, C. Ronald .

DIABETES, 2006, 55 (07) :2032-2041

[10] An assessment of self-reported physical activity instruments in young people for population surveillance: Project ALPHA [J].

Biddle, Stuart J. H. ;

Gorely, Trish ;

Pearson, Natalie ;

Bull, Fiona C. .

INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY, 2011, 8

← 1 2 3 4 5 6 7 8 9 10 →