Bortezomib-based treatment for relapsed and refractory angioimmunoblastic T-cell lymphoma: Case report and literature review

被引：4
作者：
Liu, Shuyan [1 ]
Yuan, Zhengang [1 ]
Zhang, Chunyang [1 ]
Fu, Weijun [1 ]
Hou, Jian [1 ]
机构：
[1] Second Mil Med Univ, Shanghai Changzheng Hosp, Dept Hematol, Shanghai 200003, Peoples R China
来源：
ONCOLOGY LETTERS | 2012年 / 4卷 / 02期
关键词：
bortezomib; treatment; relapsed; refractory; angioimmunoblastic T cell lymphoma; PHASE-II TRIAL; KAPPA-B; CHOP;
D O I：
10.3892/ol.2012.724
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Angioimmunoblastic T-cell lymphoma (AITL) is a distinct peripheral T-cell lymphoma (PTCL) subtype, accounting for 15-20% of PTCL and 2% of all non-Hodgkin lymphoma (NHL), with a poor prognosis. In the present study, we describe a 76-year-old patient with AITL who failed to respond to conventional chemotherapy but responded to bortezomib-based treatment and demonstrated persistent clinical improvement at the 18-month follow-up. These data suggest that bortezomib-based treatment may be a reliable, safe and effective alternative for treating relapsed/refractory AITL.
引用
收藏
页码：262 / 264
页数：3
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