Radiotherapy for Oligometastatic Non-Small Cell Lung Cancer: Past, Present, and Future

被引：1

作者：

McCall, Neal S. ^{[1
]}

Higgins, Kristin A. ^{[2
,3
]}

机构：

[1] Emory Winship Canc Inst Atlanta, Dept Radiat Oncol, Atlanta, GA 30322 USA

[2] Emory Univ, Sch Med, Dept Radiat Oncol, Atlanta, GA USA

[3] Winship Canc Inst, Emory Clin, Radiat Oncol, Clifton Campus Locat, Atlanta, GA USA

来源：

ONCOLOGY-NEW YORK | 2021年 / 35卷 / 06期

关键词：

Non-small cell lung cancer; oligometastatic; stereotactic body radiotherapy; local ablative therapy;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Historically, patients with stage IV non-small cell lung cancer (NSCLC) have been treated with chemotherapy alone, reserving local therapies for symptom palliation. However, evidence has accumulated that a subset of patients with oligometastatic NSCLC (OM-NSCLC) may benefit from local ablative therapies (LATs). In this article, we review the data that have formed the rationale for LAT, specifically radiotherapy, and the prospective trials that support its use in this population. Finally, we examine the evolving role of LAT in patients with OM-NSCLC in the context of immunotherapy and targeted therapies, as well as discuss ongoing clinical trials incorporating LAT in these patients.

引用

页码：311 / 319

页数：9