Effect of surface modification and UVA photoactivation on antibacterial bioactivity of zinc oxide powder

被引：30

作者：

Ann, Ling Chuo ^{[1
]}

Mahmud, Shahrom ^{[1
]}

Bakhori, Siti Khadijah Mohd ^{[1
]}

Sirelkhatim, Amna ^{[1
]}

Mohamad, Dasmawati ^{[2
]}

Hasan, Habsah ^{[3
]}

Seeni, Azman ^{[4
]}

Rahman, Rosliza Abdul ^{[3
]}

机构：

[1] Univ Sains Malaysia, Sch Phys, Nano Optoelect Res NOR Lab, George Town 11800, Malaysia

[2] Univ Sains Malaysia, Sch Dent Sci, Kubang Kerian 16150, Kelantan, Malaysia

[3] Univ Sains Malaysia, Sch Med Sci, Kubang Kerian 16150, Kelantan, Malaysia

[4] Univ Sains Malaysia, Adv Med & Dent Inst, Bertam 13200, Pulau Pinang, Malaysia

来源：

APPLIED SURFACE SCIENCE | 2014年 / 292卷

关键词：

Annealing; UVA; Antibacterial; Conductance; Reactive oxygen species; ZNO THIN-FILMS; BACTERIA; HYDROGEN; SLURRY; SIZE;

D O I：

10.1016/j.apsusc.2013.11.152

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The effects of surface modification of zinc oxide (ZnO) powder and UVA illumination on the powder towards Escherichia coli and Staphylococcus aureus were investigated. FESEM-EDS results showed that oxygen annealing increased the 0:Zn ratio on the surface of ZnO-rod and ZnO-plate samples. Surface conductances of ZnO-rod and ZnO-plate pellets were reduced from 1.05nS to 0.15nS and 1.34nS to 0.23 nS, respectively. Meanwhile, UVA illumination on the surface of the ZnO-rod and ZnO-plate samples was found to improve surface conductance to 7.08 nS and 6.51 nS, respectively, due to the release of charge carrier. Photoluminescence results revealed that oxygen annealing halved the UV emission intensity and green emission intensity, presumably caused by oxygen absorption in the ZnO lattice. The antibacterial results showed that oxygen-treated ZnO exhibited slightly higher growth inhibition on E. coli and S. aureus compared with unannealed ZnO. UVA illumination on ZnO causes the greatest inhibition toward E. coli and S. aureus. Under the UVA excitation, the inhibition of E. coli increased by 18% (ZnO-rod) and 13% (ZnO-plate) while the inhibition of S. aureus increased by 22% (ZnO-rod) and 21% (ZnO-plate). Release of reactive oxygen species were proposed in antibacterial mechanisms, which were aided by surface modification and UVA photoactivation. The reactive oxygen species disrupted the DNA and protein synthesis of the bacterial cell, causing bacteriostatic effects toward E. coli and S. aureus. (C) 2013 Elsevier B.V. All rights reserved.

引用

页码：405 / 412

页数：8

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