Magnetic resonance imaging-based brain tumor grades classification and grading via convolutional neural networks and genetic algorithms

Gliomas are the most common type of primary brain tumors in adults and their early detection is of great importance. In this paper, a method based on convolutional neural networks (CNNs) and genetic algorithm (GA) is proposed in order to noninvasively classify different grades of Glioma using magnetic resonance imaging (MRI). In the proposed method, the architecture (structure) of the CNN is evolved using GA, unlike existing methods of selecting a deep neural network architecture which are usually based on trial and error or by adopting predefined common structures. Furthermore, to decrease the variance of prediction error, bagging as an ensemble algorithm is utilized on the best model evolved by the GA. To briefly mention the results, in one case study, 90.9 percent accuracy for classifying three Glioma grades was obtained. In another case study, Glioma, Meningioma, and Pituitary tumor types were classified with 94.2 percent accuracy. The results reveal the effectiveness of the proposed method in classifying brain tumor via MRI images. Due to the flexible nature of the method, it can be readily used in practice for assisting the doctor to diagnose brain tumors in an early stage. (C) 2018 Nalecz Institute of Biocybernetics and Biomedical Engineering of the Polish Academy of Sciences. Published by Elsevier B.V. All rights reserved.