Batch introduction techniques

被引:2
作者
Jiménez, CR [1 ]
机构
[1] Univ Calif San Francisco, Dept Pharmaceut Chem, San Francisco, CA 94143 USA
来源
MASS SPECTROMETRY: MODIFIED PROTEINS AND GLYCOCONJUGATES | 2005年 / 405卷
关键词
D O I
10.1016/S0076-6879(05)05002-0
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Mass spectrometry (MS) is widely used as a rapid tool for peptide profiling and protein identification. However, the success of the method is compromised by dirty and contaminated samples. Moreover, analysis from a small sample volume with a relative high concentration is usually required. In this chapter, different microscale sample preparation methods are discussed for off-line, matrix-assisted laser desorption/ionization (MALDI) and nanoelectrospray ionization (nanoESI) MS analysis.
引用
收藏
页码:36 / 49
页数:14
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